Influence of Bicarbonate on the Renal Handling of Magnesium

  • N. L. M. Wong
  • G. A. Quamme
  • J. H. Dirks
Conference paper


Metabolic acidosis has been shown to increase the urinary excretion of calcium, but the effects of acidosis on renal magnesium excretion are variable. Increases in urinary magnesium have been demonstrated in some1,3 but not all studies of experimental metabolic acidosis in humans4,5. The reason for these contrasting results is not apparent. On the other hand, acute administration of acid in experimental animals failed to increase urinary magnesium6.


Metabolic Acidosis Fractional Excretion Distal Tubule Metabolic Alkalosis Chronic Metabolic Acidosis 
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  1. 1.
    F. K. Jabir, S. D. Roberts and R. A. Somersley, Clin. Sci. 16:119 (1957).PubMedGoogle Scholar
  2. 2.
    A. G. Hills, D. W. Parsons, G. O. Webster, Jr., O. Rosenthal, and H. Conover, J. Clin. Endocrinol. 19:1192 (1959).CrossRefGoogle Scholar
  3. 3.
    H. E. Martin and R. Jones, Am. Heart J. 62:206 (1961).PubMedCrossRefGoogle Scholar
  4. 4.
    E. J. Lennon and W. F. Piering, J. Clin. Invest. 49:1458 (1970).PubMedCrossRefGoogle Scholar
  5. 5.
    R. J. McCollister, A. S. Prasad, R. P. Doe, and E. B. Flink, J. Lab. Clin. Med. 57:928 (1958).Google Scholar
  6. 6.
    D. R. Roy, L. K. Blouch, and R. L. Jamison, Am. J. Physiol. 243:F197 (1982).PubMedGoogle Scholar
  7. 7.
    R. A. L. Sutton, N. L. M. Wong, and J. H. Dirks, Kidney Int. 15:520 (1971).CrossRefGoogle Scholar
  8. 8.
    J. H. Dirks, W. J. Cirksema, and R. W. Berliner, J. Clin. Invest. 44:1160 (1965).PubMedCrossRefGoogle Scholar
  9. 9.
    N. L. M. Wong, G. A. Quamme, R. A. L. Sutton, and J. H. Dirks, J. Lab. Clin. Med. 94:683 (1979).PubMedGoogle Scholar
  10. 10.
    G. G. Vurek, D. G. Warnock, and R. Coisey, Analyt. Chem. 47:765 (1975).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • N. L. M. Wong
    • 1
  • G. A. Quamme
    • 1
  • J. H. Dirks
    • 1
  1. 1.Dept. of MedicineHealth Sciences Centre Hospital University of British ColumbiaVancouverCanada

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