Intestinal Absorption of Calcium, Magnesium, Phosphate and Oxalate: Deviation from Normal in Idiopathic Urolithiasis

  • C. Y. C. Pak
  • M. J. Nicar
  • G. J. Krejs
Conference paper


There is increasing evidence that intestinal absorption of stone-forming substances may be disturbed in many patients with calcium nephrolithiasis. This disturbance in intestinal absorption in such patients is usually metabolic in origin, although it may be modified by dietary aberrations. The resulting aberration in urinary composition may lead or contribute to stone formation.


Magnesium Absorption Intestinal Calcium Absorption Oxalate Absorption Idiopathic Hypercalciuria Calcium Nephrolithiasis 
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  1. 1.
    J. S. Fordtran, Gastroenterol. 56:987 (1969).Google Scholar
  2. 2.
    C. Y. C. Pak and J. S. Fordtran, in: “Gastrointestinal Disease”, M. H. Sleisenger, J. S. Fordtran, and F. J. Ingelfinger, eds., W. B. Saunders, Philadelphia (1978).Google Scholar
  3. 3.
    G. J. Krejs, M. J. Nicar, J. E. Zerwekh, D. A. Norman, M. G. Kane, and C. Y. C. Pak, Am. J. Med. 75:973 (1983).PubMedCrossRefGoogle Scholar
  4. 4.
    W. C. Grinstead, C. Y. C. Pak, and G. J. Krejs, Am. J. Physiol. (in press).Google Scholar
  5. 5.
    P. G. Brannan, P. Vergne-Marini, C. Y. C. Pak, A. R. Hull, and J. S. Fordtran, J. Clin. Invest. 57:1412 (1976).PubMedCrossRefGoogle Scholar
  6. 6.
    G. R. Davis, J. E. Zerwekh, T. F. Parker, G. J. Krejs, C. Y. C. Pak, and J. S. Fordtran, Gastroenterol. 85:908 (1983).Google Scholar
  7. 7.
    D. E. Barilla, C. Notz, D. Kennedy, and C. Y. C. Pak, Am. J. Med. 64:597 (1978).CrossRefGoogle Scholar
  8. 8.
    P. M. Zarembski and A. Hodgkinson, Clin. Chim. Acta 25:1 (1969).PubMedCrossRefGoogle Scholar
  9. 9.
    C. Y. C. Pak, M. Ohata, E. C. Lawrence, and W. Snyder, J. Clin. Invest. 54:387 (1974).PubMedCrossRefGoogle Scholar
  10. 10.
    C. Y. C. Pak, R. A. Kaplan, H. Bone, J. Townsend, and O. Waters, New Engl. J. Med. 292:497 (1975).PubMedCrossRefGoogle Scholar
  11. 11.
    P. G. Grannan, S. Morawski, C. Y. C. Pak, and J. S. Fordtran, Am. J. Med. 66:425 (1979).CrossRefGoogle Scholar
  12. 12.
    G. Johansson, U. Backman, B. Danielson, S. Ljunghall, and B. Wikstrom, Invest. Urol. 18:93 (1980).PubMedGoogle Scholar
  13. 13.
    M. J. Nicar and C. Y. C. Pak, Min. Electr. Metab. 8:44 (1982).Google Scholar
  14. 14.
    J. E. Zerwekh and C. Y. C. Pak, Metabolism 29:13 (1980).PubMedCrossRefGoogle Scholar
  15. 15.
    D. E. Barilla, J. E. Zerwekh, and C. Y. C. Pak, Min. Electr. Metab. 2:302 (1979).Google Scholar
  16. 16.
    C. Y. C. Pak and J. E. Zerwekh, Proc. Symp. Clin. Disorders Bone Min. Metab. (in press).Google Scholar
  17. 17.
    J. E. Zerwekh, C. Y. C. Pak, R. A. Kaplan, J. L. McGuire, K. Upchurch, N. Breslau, and R. Johnson, J. Clin. Endocrinol. Metab. 51: 381 (1980).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • C. Y. C. Pak
    • 1
  • M. J. Nicar
    • 1
  • G. J. Krejs
    • 1
  1. 1.Division of Mineral Metabolism, Dept. of Internal Medicine, SW Medical SchoolUniversity of Texas Health Science CenterDallasUSA

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