Microstructure of Calcium Oxalate Foreign Body Stones Produced in Rat Bladder
Implantation of a foreign body, usually a zinc disc1, in the rat bladder is a standard method of producing urinary calculi for experimental studies. The diet is modified or ethylene glycol added to the drinking water to develop a stone of the desired composition. In order to study the microscopic architecture of such stones, zinc is inappropriate since it cannot be sectioned. Therefore we used discs, 4 mm to 6 mm in diameter, made of a plastic normally used for embedding tissue for transmission electron microscopy (TEM)2.
KeywordsCalcium Oxalate Disc Surface Calcium Oxalate Monohydrate Urinary Calculus Calcium Oxalate Monohydrate
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