Magnesium and Citric Acid in the Dissolution of Struvite and Hydroxyapatite
About 20% of renal stones are composed of struvite or hydroxy-apatite. The presence of these stones, which usually occur as large staghorn calculi, may result in a reduction of kidney function because of infection and obstruction. When surgical removal of phosphatic stones is contraindicated or otherwise impossible, local irrigation with citric acid-containing solutions may be used as an alternative1. Magnesium may be useful in alleviating the symptoms of irritation of the ureter and the bladder caused by citric acid solutions2.
KeywordsCitric Acid General Internal Medicine Renal Stone Chelate Activity Perfusion Fluid
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- 2.H. I. Suby, R. M. Suby and F. Albright, J. Urol. 48:549 (1942).Google Scholar