The Additive Effects of Magnesium and Tartrate Upon Inhibition of Calcium Oxalate Crystal Formation in Whole Urine
Stone formation in southern India is said to be much rarer than in the north1, perhaps due to tamarind fruit consumption which is eaten only in the south2. Tamarind is rich in tartaric acid, a substance known to complex Ca2+ ions. Sur et al demonstrated the inhibitory effect of tartrate in diluted urine upon calcium oxalate crystal formation. The inhibition tests described here, however, have been carried out using concentrated whole urine from which urinary crystals arise naturally, and the tests extended to cover calcium phosphate crystalluria. Since magnesium is effective in reducing calcium oxalate crystal formation3, it seemed worthwhile to establish whether or not magnesium together with tartrate would either enhance the inhibitory action of tartrate or diminish it owing to magnesium tartrate complexing.
KeywordsMagnesium Hydroxide Sodium Hydroxide Oxalate Meso
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