Inhibitors of the Precipitation of Stone-Forming Urinary Constituents: are the Established Inhibitors Effective in Preventing Stone Formation and Growth or is A Moss-Covered Stone Inevitable?

  • J. D. Sallis
Conference paper


There is no concensus on the controversy concerning the nature, function or effectiveness of either natural or synthetic inhibitors in relation to urinary stone formation. Since the pioneering work of the Fleisch group in recognizinq the inhibitory potential of the urinary constituent, pyrophosphate1, the search has been escalated to find a constituent which might effectively control the development of a stone. Today, a number of natural compounds have been presented as possible candidates. Simultaneously, knowledge is advancing on inhibitor mechanisms prompting the development of synthetic compounds as hopeful therapeutic agents.


Calcium Phosphate Calcium Oxalate Amorphous Calcium Phosphate Calcium Oxalate Crystal Urinary GAGs 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • J. D. Sallis
    • 1
  1. 1.Dept. of BiochemistryUniversity of TasmaniaHobartAustralia

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