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The Conditions for Precipitation of Uric Acid and Sodium Acid Urate

  • V. Babić-Ivančić
  • H. Füredi-Milhofer
  • O. Milat
  • W. E. Brown
  • T. M. Gregory
Conference paper

Abstract

Anhydrous uric acid (H2U), uric acid dihydrate (H2U.2H2O) and sodium acid urate monohydrate (NaHU.H2O) have been detected in urinary calculi1. A positive relationship between hyperuricosuria and calcium oxalate stone formation has also been demonstrated2. This relationship could be explained by the presence in urine of a microcrystalline or colloidal form of NaHU which might adsorb the known inhibitors of crystal growth and aggregation3or induce epitaxial growth of calcium oxalate crystals4.Data on the precipitation of these solid phases from unseeded solutions are scarce and unsystematic. It would be of considerable interest to work out phase5 and precipitation diagrams6,7 that would show which solid phase may be expected under given experimental conditions. In this paper the systems: H2U-NaOH-HCl-H2O (I) and H2U-Na0H-NaCl-H20, at pH = 7.5 (II) are represented by such diagrams.

Keywords

Uric Acid Calcium Oxalate Break Curve Calcium Oxalate Crystal Colloidal Form 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • V. Babić-Ivančić
    • 1
  • H. Füredi-Milhofer
    • 1
  • O. Milat
    • 1
  • W. E. Brown
    • 1
  • T. M. Gregory
    • 2
  1. 1.“Ruder Bošković” Institute and Institute for PhysicsZagrebYugoslavia
  2. 2.National Bureau of StandardsWashingtonUSA

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