Equations Defining Urinary Crystallization Conditions with Respect to Stone-Forming Calcium Salts
Most information on the conditions favouring the crystallization of stone-forming salts in urine has been derived indirectly from computer calculations based on urinary composition1 or from experiments performed in saline solutions or in highly diluted urine2. In a comparative study, we measured inhibitory activity and the state of supersaturation with respect to calcium oxalate and calcium phosphate directly in the urine from 13 idiopathic calcium stone formers (ISF), 12 patients with primary hyperparathyroidism (HPT) and 16 healthy controls (HC)3. These results have now been analyzed mathematically to obtain equations to predict the physico-chemical behaviour of urine from the chemical composition.
KeywordsPrimary Hyperparathyroidism Calcium Oxalate Product Ratio Calcium Oxalate Monohydrate Calcium Salt
Unable to display preview. Download preview PDF.
- 1.W. G. Robertson, M. Peacock and B. E. C. Nordin, Clin, Sci. 34:579 (1968).Google Scholar
- 3.J. M. Baumann, K. Lauber, F. X. Lustenberger, M, Wacker, and E. J. Zingg, (in preparation).Google Scholar
- 7.N. A. Breslau and C. Y. C. Pak, in: “Nephrolithiasis, Contemporary Issues in Nephrology”, vol 5, B. M. Brenner and J. H. Stein, eds., Churchill Livingstone, New York (1980).Google Scholar
- 9.J. M. Baumann, S. Bisaz, R. Felix, U. Ganz, and R. G. G. Russell, Clin. Sci. 53:141 (1977).Google Scholar