A Scanning Electron Microscopy (SEM) Study of the Bladder Mucosa in Paediatric Patients with Idiopathic Calculus Disease
Idiopathic bladder calculus disease, prevalent in Thailand and many developing countries, has been characterized as a distinct subgroup of urolithiasis. It occurs predominantly in children below 10 years of age and has an uncommon association with renal calculi1. The mechanism by which the vesical calculus is formed is unclear. Heavy crystalluria of calcium oxalate, uric acid, and ammonium acid urate, noted in the children in the endemic areas, is thought to be associated with the high incidence2. Finlayson has calculated that crystal growth to a critical size is possible in the bladder3. Fixation of the crystals, noted in the kidney tubules and ducts of Bellini4, has not been observed on the bladder mucosa. It is therefore the purpose of this study to evaluate the role of the bladder mucosa in the genesis of idiopathic vesical calculi.
KeywordsCalcium Oxalate Bladder Mucosa Kidney Tubule High Power View Uric Acid Crystal
Unable to display preview. Download preview PDF.
- 1.A. Vaanamitta, in: “Urinary Calculi”, J. G. Brockis and B. Finlayson, eds., PSG Publishing Co., Littleton (1981).Google Scholar
- 3.B. Finlayson, in: “Idiopathic Urinary Bladder Stone Disease”, R. Van Reen, ed., DHEW Publication No. (NIH) 77–1063, Washington (1977).Google Scholar
- 8.A. L. Aurora, in: “Idiopathic Urinary Bladder Stone Disease”, R. Van Reen, ed., DHEW Publication NIH 77–1063, Washington.Google Scholar