Spontaneous in Vitro Generation of Oxalate from L-Ascorbate in Some Assays for Urinary Oxalate and its Prevention
Erroneously high levels of urinary oxalate were noticed in the summertime with the Sigma enzymatic oxalate assay1. It was thought that L-ascorbate might be responsible for this artifactual increase since L-ascorbate may be oxidised to oxalate via dehydroascorbate and diketogulonate2. We therefore studied this conversion in conditions used in some of the assays for urinary oxalate.
KeywordsAminobenzoic Acid Urinary Oxalate Oxalate Oxidase Oxalate Level Automate Assay
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