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The Effect of Ascorbic Acid on Urine Oxalate Measurement

  • B. C. Mazzachi
  • J. K. Teubner
  • R. L. Ryall
Conference paper

Abstract

We report that conditions employed in the pre-treatment of the urine are crucial to the correct estimation of oxalate. Interference of ascorbic acid, a common urinary constituent, has been noted in a number of different methods. After systematic investigation of the steps in our assay, we have found that this interference is associated with the pre-treatment conditions, particularly any pH adjustment with alkali, pH of precipitation, and collection and storage of urine. We describe conditions for assay which give minimal interference by ascorbic acid and which are applicable to all urinary oxalate methods.

Keywords

Ascorbic Acid Urine Collection Correct Estimation Minimal Increase Minimal Interference 
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References

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    B. C. Mazzachi, J. K. Teubner, and R. L. Ryall, Clin, Chenu 30:(1984) (in press).Google Scholar
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    C. Hughes, S. Dutton, and A. S. Truswell, J. Human Nutr. 35:274 (1981).Google Scholar
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    M. F. Laker, in: “Advances in Clinical Chemistry” Vol. 23, A. L. Latner and M. K. Schwartz, eds., Academic Press, New York (1983).Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • B. C. Mazzachi
    • 1
  • J. K. Teubner
    • 1
  • R. L. Ryall
    • 1
  1. 1.Depts. of Clinical Biochemistry and SurgeryFlinders Medical CentreBedford ParkAustralia

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