Relative Merit of Various Nonsurgical Treatments of Infection Stones in Dogs
Dietary management, urease inhibition and antibiotic treatment can control growth and recurrence of infection stones. Although urease inhibition and antibiotic treatment have also induced stone dissolution in a few patients, complete dissolution by these means is not common. Recently a stone dissolution (S/D) diet (Table 1) combined with antibiotic treatment has been shown to induce rapid dissolution of experimental and spontaneous infection stones in the dog1. Flurofamide is a novel potent urease inhibitor, excreted in the active form in the urine2. We compared the relative supersaturation of struvite (RSS) in urine when the S/D diet, flurofamide, and antibiotic treatment, alone or in combination, were given to dogs with experimental infection stone disease.
KeywordsAntibiotic Treatment Control Diet Clavulanic Acid Diet Feeding Urease Inhibition
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- 1.C. A. Osborne, S. U. Abdullahi, J. R. Leissinger, D. J. Polzin, N. E. Hauer, J. S. Klausner, R. M, Hardy, A. B. Kuzma, and C. J. Gidlund, Minn, Vet. 22:14(1982).Google Scholar
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