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Relative Merit of Various Nonsurgical Treatments of Infection Stones in Dogs

  • D. F. Senior
  • W. C. ThomasJr
  • J. M. Gaskin
  • B. Finlayson
Conference paper

Abstract

Dietary management, urease inhibition and antibiotic treatment can control growth and recurrence of infection stones. Although urease inhibition and antibiotic treatment have also induced stone dissolution in a few patients, complete dissolution by these means is not common. Recently a stone dissolution (S/D) diet (Table 1) combined with antibiotic treatment has been shown to induce rapid dissolution of experimental and spontaneous infection stones in the dog1. Flurofamide is a novel potent urease inhibitor, excreted in the active form in the urine2. We compared the relative supersaturation of struvite (RSS) in urine when the S/D diet, flurofamide, and antibiotic treatment, alone or in combination, were given to dogs with experimental infection stone disease.

Keywords

Antibiotic Treatment Control Diet Clavulanic Acid Diet Feeding Urease Inhibition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    C. A. Osborne, S. U. Abdullahi, J. R. Leissinger, D. J. Polzin, N. E. Hauer, J. S. Klausner, R. M, Hardy, A. B. Kuzma, and C. J. Gidlund, Minn, Vet. 22:14(1982).Google Scholar
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    D. E. Millner, J. A. Anderson, M. E. Appier, C. E. Benjamin, J. G. Edwards, D. T. Humphrey, and E. M. Shearer, J. Urol. 127:346 (1982).PubMedGoogle Scholar
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    B. Finlayson, in: “Calcium Metabolism in Renal Failure and Nephrolithiasis”, D. S. David, ed., Wiley, New York (1977).Google Scholar
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    I. J. Rosenstein, J. M. Hamilton-Miller, and W. Brumfitt, Infect. Immun. 32:32 (1981).PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • D. F. Senior
    • 1
  • W. C. ThomasJr
    • 1
  • J. M. Gaskin
    • 1
  • B. Finlayson
    • 1
  1. 1.Dept. of Medical SciencesCollege of Veterinary Medicine, University of FloridaGainesvilleUSA

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