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Prophylaxis of Calcium Oxalate Stones : Clinical Trials of Allopurinol, Magnesium Hydroxide and Chlorthalidone

  • B. Ettinger
  • J. T. Citron
  • A. Tang
  • B. Livermore

Abstract

Despite numerous reports of kidney stone prophylaxis, there is still considerable controversy about the effectiveness of any regimen. Most published clinical trials suffer from one or more of the following faults: (i) lack of an adequate number of subjects, (ii) lack of an adequate follow-up time, (iii) lack of an objective end-point and (iv) lack of an adequate comparison group. We decided to carry out three double-blind controlled clinical trials to test adequately the effectiveness of magnesium hydroxide, chlorthalidone or allopurinol.

Keywords

Calcium Oxalate Considerable Controversy Magnesium Hydroxide Urinary Oxalate Calcium Oxalate Stone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • B. Ettinger
    • 1
  • J. T. Citron
    • 1
  • A. Tang
    • 1
  • B. Livermore
    • 1
  1. 1.Kaiser Permanente Medical CenterSan FranciscoUSA

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