The Effect of Alkalinizing Agents on Calcium Oxalate Stone Formation in a Rat Model

  • J. G. Gregory
  • K. Y. Park
  • T. C. Burns
Conference paper

Abstract

In an attempt to determine the relative efficacy of therapy to reduce calcium oxalate stone formation in patients with enteric hyperoxaluria, the effects of the alkalinizing agents sodium bicarbonate, sodium orthophosphate and sodium citrate have been studied with an experimental animal model capable of inducing rapid enteric hyperoxaluric stone formation.

Keywords

Dioxide Citrate Bicarbonate Oxalate Na2HPo4 

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References

  1. 1.
    K. Y. Park and J. G. Gregory, Clin. Chem. 26:1170 (1980).PubMedGoogle Scholar
  2. 2.
    J. G. Gregory, K. Y. Parkf R. Wilt, and A. Feigl, in: “Urolithiasis Clinical and Basic Research”, L. H. Smith, B. Finlayson, and W. G. Robertson, eds., Plenum Press, New York (1981).Google Scholar
  3. 3.
    J. G. Gregory, M. M. Hoy, K. Y. Park, and A. Fleigl, in: “Urolithiasis Clinical and Basic Research”, L. H. Smith, B. Finlayson, and W. G. Robertson, eds., Plenum Press, New York (1981).Google Scholar
  4. 4.
    J. G. Gregory, K. Y. Park, and T. C. Burns, in: “Urolithisis and Related Clinical Research1, P. O. Schwüle, L. H. Smith, W. G. Robertson, and W. Vahlensieck, eds., Plenum Press, New York (1985).Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • J. G. Gregory
    • 1
  • K. Y. Park
    • 1
  • T. C. Burns
    • 1
  1. 1.St. Louis University School of MedicineSt. LouisUSA

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