Abstract
Thiazide diuretics and orthophosphates are generally considered effective in the prevention of recurrent calcium urolithiasis but several randomized controlled clinical trials have failed to demonstrate this effectiveness13–15. These different conclusions may, in part, be explained by the various clinical research designs used. In order to evaluate this, clinical trials using these drugs to prevent recurrent calcium urolithiasis were examined from the viewpoint of clinical research methodology.
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References
D. S. Bernstein and R. Newton, Lancet 2:1105 (1966).
E. R. Yendt, Canad. Med. Assoc. J. 102:479 (1970).
L. H. Smith, W. C. Thomas, and C. D. Arnaud, in: “Urinary Calculi”, L. Cifuentes Delatte, A. Rapado, and A. Hodgkinson, eds., Karger, Basel (1973).
B. Ettinger and F. O. Kolb, Am. J. Med. 55:32 (1973).
F. L. Coe and A. G. Kavalich, New Engl. J. Med. 291:1344 (1974).
E. R. Yendt and M. Cohanim, Kidney Int. 13:397 (1978).
M. Peacock, W. G. Robertson, P. J. Heyburn, A. E. J. Davies, and A. Rutherford, in: “Urolithiasis, Clinical and Basic Research”, L. H. Smith, W. G. Robertson, and B. Finlayson, eds., Plenum, New York (1981).
G. Maschio, N. Tessitore, A. D’Angelo, A. Fabris, F. Pagano, A. Tasca, G. Graziani, A. Aroldi, M. Suriam, G. Colussi, A. Mandressi, A. Trinchieri, F. Rocco, C. Ponticelli, and L. Minetti, Am. J. Med. 71:623 (1981).
F. L. Coe, Ann. Intern. Med. 87:404 (1977).
U. Backman, B. G. Danielson, G. Johansson, S. Ljunghall, and B. Wikström, Br. J. Urol. 51:175 (1979).
S. Ljunghall, U. Backman, B. G. Danielson, B. Fellstrom, G. Johansson, and B. Wikström, in: “Urolithiasis, Clinical and Basic Research”, L. H. Smith, W. G. Robertson, and B. Finlayson, eds., Plenum, New York (1981).
C. Y. C. Pak, P. Peters, G. Hurt, M. Kadesky, M. Fine, D. Reisman, F. Splann, C. Caramela, A. Freeman, F. Britton, K. Sakhaee, and N. A. Breslau, Am. J. Med. 71:615 (1981).
B. Ettinger, Am. J. Med. 61:200 (1976).
P. Brocks, C. Dahl, H. Wolf, and I. Transbøl, Lancet 2:124 (1981).
D. Scholz, P. O. Schwüle, and A. Sigel, J. Urol. 128:903 (1982).
C. W. Dunnett and M. Gent, Biometrics 33:593 (1977).
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© 1985 Plenum Press, New York
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Churchill, D.N. (1985). Appraisal of Methodology in Studies of Either Thiazide or Orthophosphate Therapy for Recurrent Calcium Urolithiasis. In: Schwille, P.O., Smith, L.H., Robertson, W.G., Vahlensieck, W. (eds) Urolithiasis and Related Clinical Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7272-1_102
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DOI: https://doi.org/10.1007/978-1-4684-7272-1_102
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