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Epidemiology of Urolithiasis and Calcium Metabolism in Human Diabetes Mellitus

  • W. Tschöpe
  • E. Ritz
  • M. Haslbeck
  • H. Mehnert
  • D. Deppermann
Conference paper

Abstract

It has been shown in man1 and dogs2 that, in the presence of a constant blood glucose level, administration of insulin results in an exaggerated urinary excretion of calcium and increased tubular reabsorption of phosphorus. In the diabetic state (established insulin deficiency) the hypocalciuric effect of insulopenia counteracts the hypercalciuric effect of glucose-induced osmotic diuresis3. In the present epidemiological study the prevalence of urolithiasis and hypercalciuria have been determined in diabetics and controls.

Keywords

Urinary Calcium Stone Disease Calcium Excretion Tubular Reabsorption Experimental Diabetes Mellitus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • W. Tschöpe
    • 1
  • E. Ritz
    • 1
  • M. Haslbeck
    • 1
  • H. Mehnert
    • 1
  • D. Deppermann
    • 1
  1. 1.Depts. of Internal MedicineUniversity of Heidelberg Diabetes Research, Municipal Hospital, Munchen-Schwabing, and Internal MedicineLudwigshafenGermany

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