Damage to the Developing Brain and Subtle Psychiatric Consequences: Implications of the Case of Milton: Discussion of Dr. Christ’s Paper
Dr. Christ has focused our attention on a problem of central importance, not only in the treatment of childhood malignancies, but in the broader field of psychiatry and human behavior. American psychiatry and psychology have tended to neglect the role of the neural substrate in behavior and affect. The case of Milton is a beautiful illustration of the role that insult to the central nervous system (CNS) may play, both directly and indirectly, in influencing psychological function, and of how even well-trained clinicians may ignore it as a result of their theoretical preconceptions.
KeywordsLeukemia Dementia Methotrexate Milton Hema
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