The Effects of Constant Light on Visually Guided Behavior

  • Kenneth V. Anderson
  • Vance Lemmon


Adult, albino rats kept in continuous light have been shown to develop severe retinal degeneration. Both light and electron microscopic evidence has indicated that substantial destruction occurred in the receptor cell layer when low levels of light (less than 20 Ft-C) were used to produce the degeneration (1–10) and that both the receptor cell and pigment epithelial layers were seriously damaged when high levels of light (more than 100 Ft-C) were used to induce degeneration (11–13). Incandescent lighting was only slightly less effective than fluorescent lighting in producing light-induced, retinal degeneration (8). Spectral sensitivity studies have suggested that the shorter wavelengths of visible light produce the most damaging effects on the retina (14–16).


Ganglion Cell Layer Constant Light Outer Nuclear Layer Inner Nuclear Layer Retinal Damage 
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  1. 1.
    Anderson, K. V. and O’Steen W. K. (1971) Expl. Neurol. 30, 555–564.CrossRefGoogle Scholar
  2. 2.
    Anderson, K. V. and O’Steen, W. K. (1971) Expl. Neurol. 32, 502–505.CrossRefGoogle Scholar
  3. 3.
    Anderson, K. V. and O’Steen, (1972) Expl. Neurol. 34, 446–454.CrossRefGoogle Scholar
  4. 4.
    Bennett, M. H., Dyer, R. F. and Dunn, J. D. (1972) Expl. Neurol. 34, 434–445.CrossRefGoogle Scholar
  5. 5.
    Bennett, M. H., Dyer, R. F. and Dunn, J. D. (1973). Expl. Neurol. 38, 80–89.CrossRefGoogle Scholar
  6. 6.
    O’Steen, W. K. (1970) Expl. Neurol. 27, 194–205.CrossRefGoogle Scholar
  7. 7.
    O’Steen, W. K. and Anderson, K. V. (1971) Expl. Neurol. 30, 525–534.CrossRefGoogle Scholar
  8. 8.
    O’Steen, W. K. and Anderson, K. V. (1971) Z. Zellforsch. 127, 306–313.CrossRefGoogle Scholar
  9. 9.
    O’Steen, W. K. and Lytle, R. B. (1971) Am. J. Anat. 130, 227–234.CrossRefGoogle Scholar
  10. 10.
    O’Steen, W. K., Shear, C. R. and Anderson, K. V. (1972) Am. J. Anat. 134, 5–22.CrossRefGoogle Scholar
  11. 11.
    Grignolo, A., Orzalesi, N., Castelazzo, R. and Vittone, P. (1969) Ophthalmologica, 157, 43–59.CrossRefGoogle Scholar
  12. 12.
    Kuwabara, T. and Gorn, A. (1968) Arch. Ophthal. 79, 69–78.CrossRefGoogle Scholar
  13. 13.
    Noell, W. K., Walker, V. S., Kang, B. S. and Berman, S. (1966) Invest. Ophthal. 5, 450–476.Google Scholar
  14. 14.
    Anderson, K. V., Coyle, F. P., and O’Steen, W. K. (1972) Expl. Neurol. 35, 233–238.CrossRefGoogle Scholar
  15. 15.
    Ham, W. T., Mueller, H. A. and Sliney, D. H. (1976) Nature, 260, 153–155.CrossRefGoogle Scholar
  16. 16.
    Moon, M. E., Clarke, A. M., Ruffolo, J. J., Mueller, H. A. and Ham, W. T. (1978) Vis. Res. 18, 1573–1577.CrossRefGoogle Scholar
  17. 17.
    Gorn, R. A. and Kuwabara, T. (1967) Archs. Ophthal. 77, 115–118.CrossRefGoogle Scholar
  18. 18.
    Noell, W. K. and Albrecht, R. (1971) Science, 172, 76–80.CrossRefGoogle Scholar
  19. 19.
    Kaitz, M. and Auerbach, E. (1977) Ophthal. Res. 9, 351–356.CrossRefGoogle Scholar
  20. 20.
    Rose, G. H. and Gruenau, S. P. (1973) Dev. Psychobiol. 6, 69–77.CrossRefGoogle Scholar
  21. 21.
    Lemmon, V. and Anderson, K. V. (1979) Expl. Neurol. 63, 50–75.CrossRefGoogle Scholar
  22. 22.
    Walls, G. (1942) The Vertebrate Eye, Cranbrook Institute of Science, Bloomfield Hills, Michigan.Google Scholar
  23. 23.
    Gellerman, L. W. (1933) J. Genet. Psychol. 42, 206–208.Google Scholar
  24. 24.
    Lemmon, V. and Anderson, K. V. (1979) Expl. Neurol. 63, 35–49.CrossRefGoogle Scholar
  25. 25.
    Bennet, M. H., Dyer, R. F. and Dunn, J. D. (1973) Expl. Neurol. 40, 652–660.CrossRefGoogle Scholar
  26. 26.
    LaVail, M. M. (1976) Invest. Ophthal. 15, 64–70.Google Scholar
  27. 27.
    Cicerone, C. M. (1976) Science, 194, 1183–1185.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Kenneth V. Anderson
    • 1
  • Vance Lemmon
    • 1
    • 2
  1. 1.Department of AnatomyEmory UniversityAtlantaUSA
  2. 2.Department of Physiology and BiophysicsWashington UniversitySt. LouisUSA

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