How does a Candidate Peptide Become a Hormone?

  • M. I. Grossman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 106)


Peptides, like people, have identity crises. We ask for them, as we do for ourselves, what is my role? Once we have isolated and chemically identified a peptide, we inject it and observe its various biological actions. This tells us the various things it can do. Only when we are satisfied that we have determined which of these things it actually does do when it is endogenously released under physiological conditions do we confer the title of hormone on it. A hormone is a peptide with a physiological role.


Vasoactive Intestinal Peptide Serum Gastrin Exogenous Hormone Gastrointestinal Hormone Candidate Peptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • M. I. Grossman
    • 1
  1. 1.Veterans Administration Wadsworth Hospital CenterLos AngelesUSA

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