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Radioimmunoassay of Secretin

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Gastrointestinal Hormones and Pathology of the Digestive System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 106))

Abstract

Several sensitive radioimmunoassay systems for secretin have been developed and reported1–6. The development of these assay systems depended upon the generation of a specific secretin antiserum and the iodination of secretin (natural porcine secretin, synthetic secretin or a tyrosyl derivative of secretin). This manuscript reports the results of studies conducted in our laboratory to validate a secretin radioimmunoassay.

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References

  1. Bloom SR, Ogawa O: Radioimmunoassay of human peripheral plasma secretin. J Endocrinol 58: 24, 1973

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  2. Boden G, Chey WY: Preparation and specificity of antiserum to synthetic secretin and its uses in radioimmunoassay (RIA). Endocrinology 92: 1617, 1973

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  4. Rayford PL, Curtis PJ, Fender HR, Thompson JC: Plasma levels of secretin in man and dogs: Validation of a secretin radioimmunoassay. Surgery 79: 658–665, 1976

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Author information

Authors and Affiliations

  1. Department of Surgery, The University of Texas Medical Branch, Galveston, Texas, USA

    P. L. Rayford, A. Schafmayer & J. C. Thompson

Authors
  1. P. L. Rayford
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  2. A. Schafmayer
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  3. J. C. Thompson
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Editor information

Editors and Affiliations

  1. Veterans Administration, Wadsworth Hospital Center, Los Angeles, California, USA

    Morton Grossman

  2. Institute of 3rd Surgical Pathology, University of Rome, Italy

    V. Speranza , N. Basso  & E. Lezoche ,  & 

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© 1978 Plenum Press, New York

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Rayford, P.L., Schafmayer, A., Thompson, J.C. (1978). Radioimmunoassay of Secretin. In: Grossman, M., Speranza, V., Basso, N., Lezoche, E. (eds) Gastrointestinal Hormones and Pathology of the Digestive System. Advances in Experimental Medicine and Biology, vol 106. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7248-6_38

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  • DOI: https://doi.org/10.1007/978-1-4684-7248-6_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7250-9

  • Online ISBN: 978-1-4684-7248-6

  • eBook Packages: Springer Book Archive

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