Advertisement

Immunoreactive Secretin Release and Pure Pancreatic Juice after Duodenal Infusion in Bile in Man

  • L. E. Hanssen
  • M. Osnes
  • O. Flaten
  • J. Myren
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 106)

Abstract

The improved technique of endoscopic cannulation of the main pancreatic duct has made a collection of pure pancreatic juice possible in man2,6,7,8. We have described7 an endoscopic model for the study of the exocrine pancreatic secretion after intraduodenal stimulation with test solutions. Using a side-viewing Olympus duodenoscope (model JF B2) the main pancreatic duct was cannul-ated with the standard Olympus catheter used for endoscopic cannulation. Prior to the examination another similar catheter was attached to the outside of the duodenoscope for instillation of test solutions.

Keywords

Bile Salt Pancreatic Juice Main Pancreatic Duct Pancreatic Secretion Exocrine Pancreatic Secretion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Forell MM, Otte M, Kohi HJ, Lehnert P and Stahlheber HP: The influence of bile and pure bile salts on pancreatic secretion in man. Scand. J. Gastroent, 6, 261–266, 1971PubMedCrossRefGoogle Scholar
  2. 2.
    Hanssen LE, Osnes M and Myren J. The exocrine pancreatic secretion obtained by endoscopic cannulation of the main pancreatic duct and secretin release after duodenal acidification in man. Scand. J. Gastroent., 1977, in pressGoogle Scholar
  3. 3.
    Hanssen LE and Torjesen P. Radioimmunoassay of secretin in human plasma. Scand. J. Gastroent. 12, 481–488, 1977PubMedCrossRefGoogle Scholar
  4. 4.
    Malagelada JR, DiMagno EP, Summerskill WHJ and Go VLM. Regulation of pancreatic and gallbladder function by intraluminal fatty acids and bile salts in man. J. Clin. Invest. 58, 493–499, 1976PubMedCrossRefGoogle Scholar
  5. 5.
    Melanby J. The secretion of pancreatic juice. J. Physiol, (Lond.) 61, 419–435, 1926Google Scholar
  6. 6.
    Osnes M, Hanssen LE, Flaten O and Myren J. The exocrine pancreatic secretion and immunoreactive secretin (1RS) release after intraduodenal instillation of bile in man. Gut, 1977, in pressGoogle Scholar
  7. 7.
    Osnes M, Hanssen LE and Myren J. An endoscopic method for the study of the exocrine pancreatic secretion in man. Endoscopy, 8, 124–126, 1976CrossRefGoogle Scholar
  8. 8.
    Robberrecht P, Cremer M, Vandermeers A, Vandermeers-Piret MC, Cotton P, De Neef P and Christophe J. Pancreatic secretion of total protein and of three hydrolases collected in healthy subjects via duodenoscopic cannulation. Effects of secretin, pancreozymin, and caerulein. Gastroenterology 69, 374–379, 1975Google Scholar
  9. 9.
    Wormsley KG. Stimulation of pancreatic secretion by intraduodenal infusion of bile salts. Lancet 2, 586–588, 1970PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • L. E. Hanssen
    • 1
  • M. Osnes
    • 1
  • O. Flaten
    • 1
  • J. Myren
    • 1
  1. 1.Research Laboratory of Gastroenterology, Dept. IX Internal MedicineUllevål HospitalOsloNorway

Personalised recommendations