Antral G Cells and Mucosal Gastrin Concentration in Normal Subjects and in Patients with Duodenal Ulcer
The increase of serum gastrin after a protein rich meal,1–2 insulin hypoglycaemia3 and sham feeding4 is higher in duodenal ulcer patients than in normal subjects. This may result from an increased number of antral G cells and/or from an increased antral gastrin content. Previous reports in this field have led to contradictory results. From a methodological point of view, it is still questionable if the antral gastrin content or the G cell count determined from a few antral bipsy specimens can be representative of the whole endocrine area of the antrum.
KeywordsDuodenal Ulcer Serum Gastrin Duodenal Ulcer Patient Antral Mucosa Gastrin Release
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