Antral G Cells and Mucosal Gastrin Concentration in Normal Subjects and in Patients with Duodenal Ulcer

  • L. Barbara
  • G. Biasco
  • M. Salera
  • F. Baldi
  • G. Di Febo
  • M. Miglioli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 106)


The increase of serum gastrin after a protein rich meal,1–2 insulin hypoglycaemia3 and sham feeding4 is higher in duodenal ulcer patients than in normal subjects. This may result from an increased number of antral G cells and/or from an increased antral gastrin content. Previous reports in this field have led to contradictory results. From a methodological point of view, it is still questionable if the antral gastrin content or the G cell count determined from a few antral bipsy specimens can be representative of the whole endocrine area of the antrum.


Duodenal Ulcer Serum Gastrin Duodenal Ulcer Patient Antral Mucosa Gastrin Release 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • L. Barbara
    • 1
  • G. Biasco
    • 1
  • M. Salera
    • 1
  • F. Baldi
    • 1
  • G. Di Febo
    • 1
  • M. Miglioli
    • 1
  1. 1.Cattedra di GastroenterologiaUniversità di BolognaBolognaItaly

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