Brain Nucleotides and Excitatory Processes

  • V. Bonavita
  • F. Piccoli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 13)


The trivial analogy in the structure of barbiturates and pyrimidines has suggested a series of studies, which were undertaken in our Laboratory since 1961 (Bonavita et al., 1960 to investigate on the role of some free nucleotides in cerebral activity.


Specific Radioactivity Sensorial Deprivation Maximal Electroshock Seizure Pyrimidine Nucleotide Convulsant Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. (1).
    Bonavita, V., Scarano, E., and Zito, M. Acta Neurol. 16: 493 (1961).Google Scholar
  2. (2).
    Mandel, P., and Weill, J.D. J. Physiol. (Paris) 54: 190 (1962).Google Scholar
  3. (3).
    Piccoli, F., Camarda, R. and Bonavita, V. J. Neurochem. 16: 159 (1969).PubMedCrossRefGoogle Scholar
  4. (4).
    Piccoli, F., Camarda, R., and Bonavita, V. In preparation (1970a).Google Scholar
  5. (5).
    Guarnen’, R., Piccoli, F., Camarda, R., and Bonavita, V. In preparation (1970).Google Scholar
  6. (6).
    Piccoli, F., Guarneri, R.. Camarda, R., and Bonavita, V. In preparation (1970b).Google Scholar
  7. (7).
    Bonavita, V. in Atti XVI Congresso di Neurologia Vol. 4, p- 31, M Pensiero Scientifico, Roma (l907).Google Scholar
  8. (8).
    Jacob, M., and Mandel, P. in Protides of the biological Fluids (Ed. H. Peeters) p. 63, Elsevier, Amsterdam (1966).Google Scholar
  9. (9).
    Sherrington, C. The Integrative Action of the Nervous System. Yale University Press, New Haven (1947).Google Scholar
  10. (10).
    Bonavita, V. Monaco, P., and Tripi, E., Acta Neurol. 19:215 (1964).Google Scholar
  11. (11).
    Nelson, S. R., Schulz, D. W., Passonneau, J.V., and Lowry, O. H. J. Neurochem. 15: 1271 (1968).PubMedCrossRefGoogle Scholar
  12. (12).
    Munch-Peterson, A., Kalckar, H. M., Cutolo, E., and Smith, E. E. B. Nature 172: 1036 (1953).CrossRefGoogle Scholar
  13. (13).
    Mandel, P. in Handbook of Neurochemistry, Vol. 5 (in press) (Ed. A. Lajtha). Plenum Press (1970).Google Scholar
  14. (14).
    Bondy, C. S., and Margolis, F. L. Expt I. Neurol. 27: 344 (1970).CrossRefGoogle Scholar
  15. (15).
    Wegener, G. Expt I. Brain Res. 10: 363 (1970).Google Scholar
  16. (16).
    Margolis, F.L., and Bondy, C.S. Expt I. Neurol. 27: 353 (1970).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • V. Bonavita
    • 1
  • F. Piccoli
    • 1
  1. 1.Department of NeurologyUniversity of PalermoPalermoItaly

Personalised recommendations