Oryctolagus cuniculus (n=21 + X + Y) The domestic rabbit featured prominently in the early days of mammalian genetics but this popularity has waned in recent decades. This has reflected upon the rate of discovery of mutants for the species and upon the number of known linkage groups. Despite this, the rabbit still remains a useful research animal for a variety of topics. Some 45–50 mutant gene/loci have been reported, of which 34 have been employed in studies of independent assortment and linkage. A detailed collation of early work is presented by Robinson (1956).


Linkage Group Coat Colour Chiasma Frequency Oryctolagus Cuniculus Double Crossover 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. ALBERS, J. J. and DRAY, S. (1968). Identification and genetic control of two rabbit low density lipoprotein allotypes. Biochem. Genet., 2, 25–35.PubMedCrossRefGoogle Scholar
  2. ALBERS, J. J. and DRAY, S. (1969). Identification of genetic control of two new low-density lipoprotein allotypes: phenogroups of the Lpq locus. J. Immunol, 103, 155–162.PubMedGoogle Scholar
  3. ALBERS, L. V., DRAY, S. and Knight, K. L. (1969). Allotypes and isozymes of rabbit alpha aryl esterase. Allelic products with different enzymatic activities for the same substrates. Biochemistry, 8, 4416–4424.PubMedCrossRefGoogle Scholar
  4. ASSHETON, R. (1910). Observations on crossing wild rabbits with certain tame breeds. Guy’s Hospital Rep., 64, 313–342.Google Scholar
  5. CARVALHO, A. A. M. S., de and MALAQUIAS, M. I. C. O. (1961). Gontribucias para o estudio do cariotipo do Lepus cuniculus. FoliaAnat. Univ. Conimbrigensis, 35 (9), 6 pp.Google Scholar
  6. CASTLE, W. E. (1905). Heredity of coat characters in guinea-pigs and rabbits. Car. Inst. Wash. Pub., 23.Google Scholar
  7. CASTLE, W. E. (1919). Studies of heredity in rabbits, rats and mice. Car.Inst. Wash. Pub., 288, 4–28.Google Scholar
  8. CASTLE, W. E. (1920). Linked genes in rabbits. Science, 52, 156–157.PubMedCrossRefGoogle Scholar
  9. CASTLE, W. E. (1921). More linked genes in rabbits. Science, 54, 634–636.PubMedCrossRefGoogle Scholar
  10. CASTLE, W. E. (1922). Genetic studies of rabbits and rats. Car. Inst.Wash. Pub., 320, 1–50.Google Scholar
  11. CASTLE, W. E. (1924a). Linkage of Dutch, English and Angora in rabbits. Proc. Nat. Acad. Set. U.S.A., 10, 107–108.CrossRefGoogle Scholar
  12. CASTLE, W. E. (1924b). Occurrence in rabbits of linkage in inheritance between albinism and brown pigmentation. Proc. Nat. Acad. Sci.U.S.A., 10, 486–488.CrossRefGoogle Scholar
  13. CASTLE, W. E. (1926). Studies of colour inheritance and of linkage in rabbits. Car. Inst. Wash. Pub., 337, 3–47.Google Scholar
  14. CASTLE, W. E. (1929a). The rex rabbit. J. Hered., 20, 193–199.Google Scholar
  15. CASTLE, W. E. (1929b). Linkage studies in Castorrex rabbits. Z. Ind. Abst. Vererbgsl., 52, 53–60.Google Scholar
  16. CASTLE, W. E. (1932). English and Dutch spotting and the genetics of the Hotot rabbit. Car. Inst. Wash. Pub., 427, 3–13.Google Scholar
  17. CASTLE, W. E. (1933a). The Furless rabbit. J. Hered., 24, 81–86.Google Scholar
  18. CASTLE, W. E. (1933b). The linkage relations of yellow fat in rabbits. Proc. Nat. Acad. Sci. U.S.A., 19, 947–950.CrossRefGoogle Scholar
  19. CASTLE, W. E. (1934a). Size inheritance in rabbits; further data on the backcross to the small race. J. Exp. Zool., 67, 105–114.CrossRefGoogle Scholar
  20. CASTLE, W. E. (1934b). Genetics of the Dutch pattern. J. Exp. Zool., 68, 377–391.CrossRefGoogle Scholar
  21. CASTLE, W. E. (1936). Further data on linkage in rabbits. Proc. Nat.Acad. Sci. U.S.A., 22, 222–225.CrossRefGoogle Scholar
  22. CASTLE, W. E. and KEELER, C. F. (1933). Tests for linkage between the blood group genes and other known genes in the rabbit. Proc. Nat.Acad. Sci. U.S.A., 19, 98–100.CrossRefGoogle Scholar
  23. CASTLE, W. E. and LAW, L. W. (1936). Satin, a new hair mutation in the rabbit. J. Hered., 27, 235–240.Google Scholar
  24. CASTLE, W. E. and NACHTSHEIM, H. (1933). Linkage interrelations of three genes for rex (short) coat in the rabbit. Proc. Nat. Acad. Sci.U.S.A., 19, 1006–1011.CrossRefGoogle Scholar
  25. CASTLE, W. E. and SAWIN, P. B. (1941). Genetic linkage in the rabbit. Proc. Nat. Acad. Sci. U.S.A., 27, 519–523.CrossRefGoogle Scholar
  26. CASTLE, W. E., WALTER, H. E., MULLENIX, R. C. and COBB, S. (1909). Studies of inheritance in rabbits. Car. Inst. Wash. Pub., 114.Google Scholar
  27. CHIAO, J. W. and DRAY, S. (1969). Identification and genetic control of rabbit haptoglobin allotypes. Biochem. Genet, 3, 1–13.CrossRefGoogle Scholar
  28. CHIARELLI, B., CARLI, L. de and NUZZO, F. (1962). Analisi morfometrica dei cromosomi del coniglio. Caryologica, 15, 565–568.Google Scholar
  29. CLAUSEN, J. J. and SYVERTON, J. T. (1962). Comparative chromosomal study of 31 cultured mammalian cell lines. J. Nat CancerInst, 28, 117–145.Google Scholar
  30. CONWAY, T. P., DRAY, S. and LICHTER, E. A. (1969). Identification and genetic control of three rabbit gamma-A immunoglobin allotypes. J. Immunol., 102, 544–554.PubMedGoogle Scholar
  31. DAVE, M. J., Takagi, N., Oishi, H. and Kikuchi, Y. (1965). Chromosome studies on the hare and rabbit. Proc. Japan Acad., 41, 244–248.Google Scholar
  32. DRAY, S. (1963). Genetics of gamma-globulin. Proc. XI Inter. Congr.Genet., 2, 165–180.Google Scholar
  33. DRAY, S., YOUNG, G. O. and GERALD, L. (1963). Immunological identification and genetics of rabbit allotypes. J. Immunol, 91, 403–415.PubMedGoogle Scholar
  34. DUBISKI, S. (1969). Immunochemistry and genetics of a ‘new’ allotypic specificity Ae14 of rabbit gamma-G immunoglobins: recombination in somatic cells. J. Immunol., 103, 120–128.PubMedGoogle Scholar
  35. DUBISKI, S., RAPACZ, J. and DUBINSKA, A. (1962). Heredity of rabbit gamma-globilun iso-antigens. Acta Genet. Stat. Med., 12, 136–155.Google Scholar
  36. GILMAN-SACHS, A., MAGE, R. G., YOUNG, G. O., ALEXANDER, C. and DRAY, S. (1969). Identification and genetic control of two rabbit immunoglobulin allotypes at a second light chain locus, the c locus. J. Immunol., 103, 1159–1167.PubMedGoogle Scholar
  37. HAMERS, R., HAMERS-CASTERMAN, C. and LAGNAUX, S. (1966). A new allotype in the rabbit linked with Asl which may characterize a new class of IgC. Immunology, 10, 399–408.Google Scholar
  38. HURST, C. C. (1905). Experimental studies on heredity in rabbits. Linn.Soc. J. Zool., 29, 283–324.CrossRefGoogle Scholar
  39. ISSA, M., ATHERTON, G. W. and BLANK, C. E. (1968). The chromosomes of the domestic rabbit. Cytogenetics, 7, 361–375.PubMedCrossRefGoogle Scholar
  40. KELUS, A. S. and GELL, P. G. H. (1963). Immunogenetics of rabbit gammaglobulin. Proc. XI Inter. Congr. Genet., 1, 194.Google Scholar
  41. KELUS, A. S. and GELL, P. G. H. (1967). Immunoglobulin allotypes of experimental animals. Progr. Allergy, 11, 141–184.Google Scholar
  42. KNIGHT, K. L. and DRAY, S. (1968). Identification and genetic control of two rabbit a2 -macroglobulin allotypes. Biochemistry 7, 1165–1171.PubMedCrossRefGoogle Scholar
  43. KNOPFMACHER, H. P. (1942). Thesis: Brown University.Google Scholar
  44. MELANDER, Y. (1956). The chromosome complement of the rabbit. Hereditas, 42, 432–435.CrossRefGoogle Scholar
  45. MYERS, L. B., O’LEARY, J. L. and FOX, R. R. (1964). Classification of chromosomes in normal and ataxic rabbits. Neurology, 14, 1058–1065.PubMedCrossRefGoogle Scholar
  46. NACHTSHEIM, H. (1929). Das Rexkaninchen und seine Genetik. Z. Ind.Abst. Vererbgsl., 52, 1–52.Google Scholar
  47. NICHOLS, W. W., LEVAN, A., HANSEN-MELANDER, E. and MELANDER, Y. (1965). The idiogram of the rabbit. Hereditas, 35, 63–76.Google Scholar
  48. PAP, E. (1921). Vererbung von Farbe und Zeichnung bei dem Kaninchen. Z. Ind. Abst. Vererbgsl., 26, 185–270.Google Scholar
  49. PARKHURST, R. T. and WILSON, W. K. (1933). Rexing the lilac rabbit. J. Hered., 24, 35–39.Google Scholar
  50. PEASE, M. S. (1928). Yellow fat in rabbits, a linked character? Verh. V.Intern. Kongr. Vererbungswissenschaft, 2, 1153–1156.Google Scholar
  51. PICKARD, J. N. (1941). Waved — a new coat type in rabbits. J. Genet, 42, 215–222.CrossRefGoogle Scholar
  52. PRUNERIAS, M., JACQUEMONT, C. and MATHIVON, M. F. (1965). Etudes sur les relations virus-chromosomes. V. Le caryotype du lapin domestique. Ann. Inst. Pasteur, 109, 465–471.Google Scholar
  53. PUNNETT, R. C. (1912). Inheritance of coat colour in rabbits. J. Genet, 2, 221–238.CrossRefGoogle Scholar
  54. PUNNETT, R. C. (1915). Further experiments on the inheritance of coat colour in rabbits. J. Genet, 5, 38–50.CrossRefGoogle Scholar
  55. PUNNETT, R. C. (1924). On the Japanese rabbit. J. Genet, 14, 225–240.CrossRefGoogle Scholar
  56. PUNNETT, R. C. (1926). Note on a Chinchilla-Japanese cross in rabbits. J. Genet, 17, 217–220.CrossRefGoogle Scholar
  57. PUNNETT, R. C. (1928). Further notes on Dutch and English rabbits. J. Genet, 20, 247–260.CrossRefGoogle Scholar
  58. PUNNETT, R. C. (1930). On the series of allelomorphs connected with the production of black pigment in rabbits. J. Genet, 23, 265–274.CrossRefGoogle Scholar
  59. RAY, M. and WILLIAMS, T. W. (1966). Karyotype of rabbit chromosomes from leucocyte cultures. Canad. J. Genet Cytol., 8, 393–397.Google Scholar
  60. RIFAAT, O. M. (1954). A revised map of the fifth chromosome of the domestic rabbit. Heredity, 8, 107–116.CrossRefGoogle Scholar
  61. ROBINSON, R. (1951). Dutch-type white-spotting in rabbits. Nature, 168, 300.PubMedCrossRefGoogle Scholar
  62. ROBINSON, R. (1953). Segregation of the satin gene in the rabbit. J. Hered., 44, 95–96.Google Scholar
  63. ROBINSON, R. (1956). A review of independent and linked segregation in the rabbit. J. Genet, 54, 358–369.CrossRefGoogle Scholar
  64. RROBINSON, R. (1958). Genetic studies of the rabbit. Bibliogr. Genet, 17, 229–558.Google Scholar
  65. SAWIN, P. B. (1934). Linkage of wide-band and agouti genes. J. Hered., 25, 477–481.Google Scholar
  66. SAWIN, P. B. (1955). Recent genetics of the domestic rabbit. Advanc.Genet, 7, 183–226.Google Scholar
  67. SAWIN, P. B. and GLICK, D. (1943). Atropinesterase, a genetically determined enzyme in the rabbit. Proc. Nat Acad. Sci. U.S.A., 29, 55–59.CrossRefGoogle Scholar
  68. SAWIN, P. B., GRIFFIN, M. A. and STUART, C. A. (1944). Genetic linkage of blood types in the rabbit. Proc. Nat. Acad. Sci. U.S.A., 30, 217–221.CrossRefGoogle Scholar
  69. SCHIFF, R. and STORMONT, C. (1968). The genetic control of rabbit red cell esterase variation. Proc.XII Inter. Congr. Genet, 1, 127.Google Scholar
  70. SCHIFF, R. and STORMONT, C. (1970). The biochemical genetics of rabbit erythrocyte esterases: two new esterase loci. Biochem. Genet, 4, 11–23.PubMedCrossRefGoogle Scholar
  71. SHARMA, G. P., PARSHAD, R. and GHUMAN, S. K. (1963). On the meiotic and somatic chromosomes of the rabbit. Res. Bull. Panjab Univ.Sci., 14, 171–173.Google Scholar
  72. SHAVER, E. L. and CARR, D. H. (1969). The chromosome complement of rabbit blastocysts in relation to the time of mating and ovulation. Canad. J. Genet Cytol., 11, 287–293.PubMedGoogle Scholar
  73. SLEEPER, H. A. (1940). Thesis: Brown University.Google Scholar
  74. SPENDLOVE, W. and ROBINSON, R. (1970). A linkage test with satin in the rabbit. Genetica, 41, 635–637.PubMedCrossRefGoogle Scholar
  75. TEPLITZ, R. and OHNO, S. (1963). Postnatal induction of ovogenesis in the rabbit. Exp. Cell Res., 31, 183–189.CrossRefGoogle Scholar
  76. ZELNIK, J. (1965). [The inheritance of coat colour and wool characters in Angora crossed with brown rex (Havana) rabbits.] Pol’nohospodarstvo, 11, 533–543.Google Scholar

Copyright information

© Springer Science+Business Media New York 1972

Authors and Affiliations

  • Roy Robinson

There are no affiliations available

Personalised recommendations