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Protection of Alcoholic Hydroxyl Groups and Glycol Systems

  • C. B. Reese

Abstract

Alcohols react with alkylating and acylating agents; they also react with other electrophiles: e.g., primary and secondary alcohols may be oxidized, and tertiary alcohols are especially susceptible to acid-catalyzed dehydration. It is therefore often necessary to protect alcoholic hydroxyl groups if it is intended to effect a chemical reaction solely at another site in a molecule. Such protection also prevents the possibility of neighbouring group participation by hydroxyl groups.

Keywords

Acidic Hydrolysis Benzyl Ether Tetrahedron Letter Carbohydrate Chemistry Allyl Ether 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Company Ltd 1973

Authors and Affiliations

  • C. B. Reese
    • 1
  1. 1.University Chemical LaboratoryCambridgeEngland

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