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Challenges in Assessing Long-Term Health Effects Studies

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Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 129))

Abstract

The assessment of long-term health effects from exposure to pesticides has been a serious challenge to research scientists for several decades. Causal inferences following exposures to pesticides and acute disease usually proceed without difficulty since the exposure and resultant disease are close in time. To the contrary, long-term health effects are much more difficult to assess and many factors related to person-place-time-agent interactions must be evaluated.

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References

  • Bond GG, Bodner KM, Sobel W, Shellenberger RJ, Flores GH (1988) Validation of work histories obtained from interviews. Am J Epidemiol 128: 343–351.

    PubMed  CAS  Google Scholar 

  • Boyle CA, DeCoufle P, O’Brien TR (1989) Long-term health consequences of military service in Vietnam. Epidemiol Rev 11: 1–27.

    PubMed  CAS  Google Scholar 

  • Brenner H, Savitz DA, Jockel K, Greenland S (1992) Effects of nondifferential exposure misclassification in ecologic studies. Am J Epidemiol 135: 85–93.

    PubMed  CAS  Google Scholar 

  • Falk F, Ricci A, Wolff MS, Godbold J, Deckers P (1992) Pesticides and polychlorinated biphenyl residues in human breast lipids and their relation to breast cancer. Arch Environ Hlth 47: 143–146.

    Google Scholar 

  • Gordis L (1988) Reviews and commentary, challenges to epidemiology in the next decade. Am J Epidemiol 128: 1–9.

    PubMed  CAS  Google Scholar 

  • Hulka BS, Wilcosky T (1988) Biological markers in epidemiologic research. Arch Environ Hlth 43: 83–89.

    Article  CAS  Google Scholar 

  • Kleinbaum DG, Kupper LL, Morgenstern H (1982) Epidemiologic research: Principles and quantitative methods. Wadsworth, Inc, Belmont, CA.

    Google Scholar 

  • Lilienfeld DE, Gallo MA (1989) 2,4-D, 2,4,5-T, and 2,3,7,8-TCDD: An overview. Epidemiol Rev 11: 28–58.

    Google Scholar 

  • Maclure KM, MacMahon B (1980) An epidemiologic perspective of environmental carcinogenesis. Epidemiol Rev 2: 91–112.

    Google Scholar 

  • Mantel N, Haenszel W (1988) Statistical aspects of the analysis of data from retrospective studies of disease. In: Buck C, Llopis A, Najera E, Terris M (eds) The challenge of epidemiology, issues and selected readings. Pan Am Health Organ, Washington, DC, pp 533–553.

    Google Scholar 

  • Nelson LM, Longstreth WT, Koepsell TD, Van Belle G (1990) Proxy respondents in epidemiologic research. Epidemiol Rev 12: 71–86.

    PubMed  CAS  Google Scholar 

  • Rothman KJ (1981) Induction and latent periods. Am J Epidemiol 114: 59–75.

    Google Scholar 

  • Savage EP, Tessari JD, Malberg JW, Wheeler HW, Bagby JR (1973) A search for polychlorinated biphenyls in human milk in rural Colorado. Bull Environ Contam Toxicol 9: 222–226.

    Article  PubMed  CAS  Google Scholar 

  • Savage EP, Keefe TJ, Mounce LM, Heaton RK, Lewis JS, Burcar PJ (1988) Chronic neurological sequelae of acute organophosphate pesticide poisoning. Arch Environ Hlth 43: 38–45.

    Article  CAS  Google Scholar 

  • U.S. Dept Health and Human Services (1991) 6th Ann Rept on Carcinogens, Nat Toxicol Prog. Research Triangle Park, NC, pp 1–461.

    Google Scholar 

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© 1992 Springer-Verlag New York, Inc.

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Savage, E.P. (1992). Challenges in Assessing Long-Term Health Effects Studies. In: Ware, G.W. (eds) Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology, vol 129. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-7106-9_5

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  • DOI: https://doi.org/10.1007/978-1-4684-7106-9_5

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-7108-3

  • Online ISBN: 978-1-4684-7106-9

  • eBook Packages: Springer Book Archive

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