Hypothalamic Regulation of FSH Secretion

  • Jon E. Levine
  • Lisa A. Conaghan
  • Ulrike Luderer
  • Frank J. Strobl
Part of the Serono Symposia USA book series (SERONOSYMP)


Differential regulation of LH and FSH secretion can be observed under a variety of physiological and experimental circumstances (1, 2). Situations in which FSH secretion is selectively augmented include the secondary FSH surge in female rats (3, 4), responses to unilateral (5) or bilateral ovariectomy (6), and the rise in FSH that occurs in hamsters with regressed testes following exposure to a long-day photoperiod (1). It is generally held that these selective increases in basal FSH levels result from either decreased inhibin feedback suppression (7–9), modulation of LHRH pulse frequency or amplitude (10), neurosecretion of an FSHRF distinct from the LHRH decapeptide (11), prolonged clearance rate of FSH (12), or a combination of two or more of these factors.


Luteinizing Hormone Luteinizing Hormone Level Luteinizing Hormone Release Estradiol Benzoate Luteinizing Hormone Pulse 
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Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • Jon E. Levine
  • Lisa A. Conaghan
  • Ulrike Luderer
  • Frank J. Strobl

There are no affiliations available

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