Effect of the LH:FSH Ratio in the Late Luteal Phase on Follicular Growth of the Next Menstrual Cycle

  • K. Aisaka
  • H. Tsuzuki
  • S. Kaneda
  • Y. Toriya
  • M. Nojima
  • K. Kokuho
  • K. Yoshida
Part of the Serono Symposia USA book series (SERONOSYMP)

Abstract

It is well known that gonadotropins play important roles in the development of ovarian follicles. Recently, the accuracy for measuring various hormones has been improved by using the specific purified monoclonal antibodies (MCA) (1, 2). It has also been pointed out that the growth of the main follicle begins during the late luteal phase of the last menstrual cycle (3, 4). The present study was performed to elucidate whether the serum gonadotropin levels in the late luteal phase affected follicular growth in the following menstrual cycle.

Keywords

Progesterone Estradiol Infertility Bromocriptine Hyperprolactinemia 

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References

  1. 1.
    Research Committee for the immunoradiometric assays of LH and FSH in Japan(Rep. Aono T). Multicentric clinical studies on immunoradiometric assays for measurement of serum LH and FSH using the pituitary gonadotropin standards. Clin Endocrinol(Tokyo) 1989; 36: 1087–97.Google Scholar
  2. 2.
    Jaakkola T, Ding YQ, Lehtinen PK, et al. The ratios of serum bioactive/immunoreactive LH and FSH in various clinical conditions with increased and decreased gonadotropin secretion. J Clin Endocrinol Metab 1990; 70: 1496–505.PubMedCrossRefGoogle Scholar
  3. 3.
    Hodgen GD. The dominant ovarian follicle. Fertil Steril 1982; 38: 281–8.PubMedGoogle Scholar
  4. 4.
    Scott RT, Jr, Hodgen GD. The ovarian follicle: life cycle of a pelvic clock. Clin Obstet Gynecol 1990; 33: 551–62.PubMedCrossRefGoogle Scholar
  5. 5.
    Ben-David M, Schenker JG. Transient hyperprolactinemia: a correctable cause of idiopathic female infertility. J Clin Endocrinol Metab 1983; 57: 442–4.PubMedCrossRefGoogle Scholar
  6. 6.
    Mori H, Aisaka K, Matsuoka R, et al. The mechanism of induction of ovulation by bromocriptine in euprolactinemic anovulation. Foria Endocrinol Jap 1985; 61: 38–47.Google Scholar
  7. 7.
    Aisaka K, Ando S, Kokuho K, et al. Effects of transient or occult hyperprolactinemia on luteal function. Foria Endocrinol Jap 1986; 62: 117–25.Google Scholar
  8. 8.
    Futterweit W. Polycystic ovarian disease. New York: Springer-Verlag, 1984: 97–111.Google Scholar
  9. 9.
    Aisaka K, Kaneda S, Tsuzuki H, et al. Comprehensive approach to clinical background and effect of bromocriptine administration in the patients of endocrinological polycystic ovarian disease. Foria Endocrinol Jap 1990; 66: 101–12.Google Scholar

Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • K. Aisaka
  • H. Tsuzuki
  • S. Kaneda
  • Y. Toriya
  • M. Nojima
  • K. Kokuho
  • K. Yoshida

There are no affiliations available

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