Expression of FSH and LH Receptor mRNAs in the Rat Ovary
The pituitary gonadotropins, follicle stimulating hormone (FSH) and luteinizing hormone (LH), play important roles in regulating the steroidogenic and gametogenic functions of the gonads. The actions of these hormones are mediated by specific cell-surface receptors, the LH/hCG receptor (LH/hCGR), and the FSH receptor (FSH-R). Cloned cDNAs for these receptors were recently isolated in several laboratories (1–4). The deduced amino acid sequences of these two receptors predicts 7 potential transmembrane domains, indicating that they are related to the G-protein-coupled receptor family.
KeywordsGranulosa Cell Thecal Cell Follicle Stimulate Hormone Receptor Degenerate Oligonucleotide Primer Testicular Receptor
Unable to display preview. Download preview PDF.