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Biological Activities of Recombinant Human Follicle Stimulating Hormone

  • Peter R. Schofield
  • Anne Cerpa-Poljak
  • Mark F. Albrecht
  • Margaret C. Stuart
  • Yvonne J. Hort
Part of the Serono Symposia USA book series (SERONOSYMP)

Abstract

Follicle stimulating hormone (FSH), a member of the glycoprotein hormone family produced in the anterior pituitary, plays a major role in the maturation of ovarian follicles. FSH is a 32-kD heterodimer consisting of 2 noncovalently linked subunits, α and β. Each subunit contains 2 asparagine-linked carbohydrate complexes that are required for full biological activity of the hormone (e.g., circulatory half-life, signal transduction, etc.). Variation in glycosylation patterns at these sites results in multiple hormone isoforms that possess differing biological activities.

Keywords

Granulosa Cell Follicle Stimulate Hormone Follicle Stimulate Hormone Level Follicle Stimulate Hormone Receptor Recombinant Follicle Stimulate Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • Peter R. Schofield
  • Anne Cerpa-Poljak
  • Mark F. Albrecht
  • Margaret C. Stuart
  • Yvonne J. Hort

There are no affiliations available

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