Prostate—An Extrapituitary Source of Follicle Stimulating Hormone

  • Seema V. Garde
  • Anil R. Sheth
Part of the Serono Symposia USA book series (SERONOSYMP)


The prostate is known to synthesize and secrete various protein hormones, growth factors and neuropeptides, that without any doubt, establish the entity of the prostate as an endocrine organ (1, 2). Our earlier studies had demonstrated the presence of a protein exhibiting inhibin-like activity—prostatic inhibin peptide (PIP)—in prostates of human (3) and animal species (4) that preferentially suppressed synthesis and release of pituitary follicle stimulating hormone (FSH). Since the synthesis and secretion of FSH and inhibin are interdependent (5) and earlier studies also indicated their coexistence in various tissues (6–8), we were prompted to look for FSH in prostates of human and animal species.


Benign Prostatic Hyperplasia Granulosa Cell Human Prostate Langur Monkey Inhibin Subunit 
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Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • Seema V. Garde
  • Anil R. Sheth

There are no affiliations available

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