Hypergonadotropic Forms of Amenorrhea

  • Robert W. Rebar
  • Janet M. Carter
  • Jung Gu Kim
  • Cynthia K. Sites
  • Dina Y. Song
  • Andrew R. LaBarbera
Part of the Serono Symposia USA book series (SERONOSYMP)


Circulating concentrations of follicle stimulating hormone (FSH) increase dramatically following both bilateral oophorectomy and the menopause. Thus, by definition, young women with hypergonadotropic amenorrhea should have premature ovarian failure (POF). This belief was based on the findings of Goldenberg et al. (1), who reported that without exception, individuals with FSH levels of greater than 40 mIU/mL 2nd IRP-hMG (International Reference Preparation-human menopausal gonadotropins) had no viable follicles on ovarian biopsy.


Ovarian Failure Premature Ovarian Failure Follicle Stimulate Hormone Level Secondary Amenorrhea Primary Amenorrhea 
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Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • Robert W. Rebar
  • Janet M. Carter
  • Jung Gu Kim
  • Cynthia K. Sites
  • Dina Y. Song
  • Andrew R. LaBarbera

There are no affiliations available

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