Follicle Stimulating Hormone and the Control of Spermatogenesis and Inhibin Secretion in Men

  • William J. Bremner
  • Alvin M. Matsumoto
Part of the Serono Symposia USA book series (SERONOSYMP)


Stimulation of the testes by the pituitary—gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH)—is necessary for spermatogenesis (1). LH binds to receptors on interstitial Leydig cells of the testis and stimulates the production of testosterone (T), which in high local concentrations is thought to be important in the initiation and maintenance of sperm production. FSH binds to receptors on Sertoli cells (Sc) and stimulates the production of a number of proteins that are thought to be important in the control of spermatogenesis. The Sc also produces inhibin, and the Leydig cell has been reported to produce both inhibin (2) and activin (3).


Leydig Cell Sperm Production Hypogonadotropic Hypogonadism Follicle Stimulate Hormone Level Gonadotropin Deficiency 
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Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • William J. Bremner
  • Alvin M. Matsumoto

There are no affiliations available

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