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Cell-Cell Interactions that Influence FSH Regulation of Testis Function

  • John N. Norton
  • Catherine Tananis Anthony
  • Michael K. Skinner
Part of the Serono Symposia USA book series (SERONOSYMP)

Abstract

Follicle stimulating hormone (FSH) is a gonadotropin secreted from the pituitary that influences the function and differentiation of the testicular Sertoli cell (Sc). This influence of FSH on Sc is mediated through activation of adenylate cyclase, followed by elevation of cAMP levels, stimulation of cAMP-dependent protein kinase, and regulation of gene expression (1–5). FSH promotes and regulates Sc function and differentiation throughout pubertal development; however, the role of FSH in the adult animal is unclear and remains to be fully elucidated.

Keywords

Nerve Growth Factor Follicle Stimulate Hormone Sertoli Cell Leydig Cell Germinal Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • John N. Norton
  • Catherine Tananis Anthony
  • Michael K. Skinner

There are no affiliations available

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