Non-Conventional Resistance to Viruses in Plants — Concepts and Risks

  • Roger Hull
Part of the Stadler Genetics Symposia Series book series (SGSS)


Viruses cause large yield losses in many crop species and, in some situations, can limit the use of certain crops in some areas. There are three basic approaches to preventing these crop losses. Firstly, the sources of virus infection can be removed, say, by use of virus-free planting stock or by eradication schemes. Secondly, attempts can be made to prevent virus spread by cultural techniques such as killing their vectors. Thirdly, virus-resistant varieties of crops can be used. This latter approach has several major advantages: it is considered to be the most economical for farmers; it reduces the ecological problems caused by the widespread use of pesticides; and it is thought to be the most effective control measure in the long term.


Coat Protein Tobacco Mosaic Virus Plant Virus Seed Transmission Barley Stripe Mosaic Virus 
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  1. Anon, 1988, “Top” seed hits snags, International Agricultural Development March/April 1988, p. 21.Google Scholar
  2. Baulcombe, D., 1989, Strategies for virus resistance, Trends in Genetics, in press.Google Scholar
  3. Baulcombe, D.G., Hamilton,W.D.O., Mayo, M.A. and Harrison, B.D., 1987, Resistance to viral disease through expression of viral genetic material from the plant genome, in “Plant Resistance to Viruses”, CIBA Foundation Symposium 133, D. Evered and S. Harnett eds., John Wiley and Sons, Chichester, pp. 170–184.Google Scholar
  4. Bol, J.F., van Huijsduijen, H., Cornelissen, B.J.C. and van Kan, J.A.L., 1987, Characterization of pathogenesis-related proteins and genes, in “Plant Resistance to Viruses”, CIBA Foundation Symposium 133, D. Evered and S. Harnett eds, John Wiley and Sons: Chichester, pp. 72–91.Google Scholar
  5. Brisco, M., Hull, R. and Wilson, T.M.A., 1986, Swelling of isometric and of bacilliform plant virus nucleocapsids is required for virus-specific protein synthesis in vitro, Virology, 148: 210.PubMedCrossRefGoogle Scholar
  6. Carrington, J.C. and Dougherty, W.G., 1988, A viral cleavage site cassette: identification of amino acid sequences required for tobacco etch virus polyprotein processing, Proc. Natl. Acad. Sci. USA, 85: 3391.PubMedCrossRefGoogle Scholar
  7. Carroll, T.C., 1972, Seed transmissibility of two strains of barley stripe mosaic virus, Virology, 48: 323.PubMedCrossRefGoogle Scholar
  8. Cuozzo, M., O’Connell, K.M., Kaniewski, W., Fang, R.-X., Chua, N.-H. and Turner, N.E., 1988, Viral protection in transgenic tobacco plants expressing the cucumber mosaic virus coat protein or its antisense RNA, Biotechnology, 6: 549.CrossRefGoogle Scholar
  9. Delauney, A.J., Tabaeizadeh, Z. and Verma, D.P.S., 1988, A stable bifunctional antisense transcript inhibiting gene expression in transgenic plants, Proc. Natl. Acad. Sci. USA, 85: 4300.PubMedCrossRefGoogle Scholar
  10. Dorssers.L., van der Krol, S., van der Meer, J., van Kammen, A. and Zabel, P., 1984, Purification of cowpea mosaic virus RNA replication complex: identification of a virus-encoded 110,000 dalton polypeptide responsible for RNA chain elongation, Proc. Natl. Acad. Sci. USA, 81: 1951.PubMedCrossRefGoogle Scholar
  11. Ecker, J.R. and Davis, R.W., 1986, Inhibition of gene expression in plant cells by expression of antisense RNA, Proc. Natl. Acad. Sci. USA, 83: 5372.PubMedCrossRefGoogle Scholar
  12. Eliopoulos, E.E., Geddes, A.J., Brett, M., Pappin, D.J.C. and Findlay, J.B.C., 1982, A structural model for the chromophore binding domain of rhodopsin, Int. J. Biol. Macromol., 4: 263.CrossRefGoogle Scholar
  13. Fraser, R.S.S., 1986, Genes for resistance to plant viruses, CRC Crit. Rev. Plant Sci., 3: 257.CrossRefGoogle Scholar
  14. Fraser, R.S.S., 1987, Genetics of plant resistance to viruses, in “Plant Resistance to Viruses”, Ciba Foundation Symposium 133, D. Evered and S. Harnett eds., John Wiley and Sons, Chichester, pp. 6–22.Google Scholar
  15. Fritig, B., Kauffmann, S., Dumas, B., Geoffroy, P., Kopp, M. and Legrand, M., 1987, Mechanism of the hypersensitivity reaction of plants, “in Plant Resistance to Viruses”, CIBA Foundation Symposium 133, D. Evered and S. Harnett eds., John Wiley and Sons: Chichester, pp. 92–108.Google Scholar
  16. Goldbach, R.W. 1986, Molecular evolution of plant RNA viruses, Ann. Rev. Phytopath., 24: 289.CrossRefGoogle Scholar
  17. Goldbach, R., 1987, Genome similarities between plant and animal RNA viruses, Microbiol. Sci., 4: 197.PubMedGoogle Scholar
  18. Goldbach, R. and van Kammen, A. 1985, Structure, replication and expression of the bipartite genome of cowpea mosaic virus, in “Molecular Plant Virology”, J.W. Davies, ed., CRC Press: Boca Raton, Florida, Vol. 2. pp. 83–120.Google Scholar
  19. Haber, S. and Hamilton, R.I., 1980, Distribution of determinants for symptom production, nucleoprotein component distribution and antigenicity of coat protein between the two RNA components of cherry leaf roll virus, J. gen. Virol., 50: 377.CrossRefGoogle Scholar
  20. Hall, T.C., Miller, W.A. and Bujarski, J.J., 1982, Enzymes involved in the replication of plant viral RNAs, Adv. Plant Pathol., 1: 179.Google Scholar
  21. Hanada, K. and Harrison, B.D., 1977, Effects of virus genotype and temperature on seed transmission of nepoviruses, Ann. appl. Biol., 85: 70.CrossRefGoogle Scholar
  22. Harrison, B.D. 1987, Plant virus transmission by vectors: Mechanisms and consequences, in “Molecular Basis of Virus Disease”, W.C. Russell and J.W. Almond, ed., Cambridge University Press: Cambridge, pp. 319–344.Google Scholar
  23. Harrison, B.D. and Hanada, K., 1976, Competitiveness between genotypes of raspberry ringspot virus is mainly determined by RNA-1, J. gen. Virol., 31: 455.CrossRefGoogle Scholar
  24. Harrison, B.D. and Murant, A.F., 1984, Involvement of virus-coded proteins in transmission of plant viruses by vectors, in “Vectors in Virus Biology”, M.A. Mayo and K.A. Harrap, ed., Academic Press: London, pp. 1–36.Google Scholar
  25. Harrison, B.D., Murant, A.F., Mayo, M.A. and Roberts, I.M., 1974, Distribution of determinants for symptom production, host range and nematode transmissibility between the two RNA components of raspberry ringspot virus, J. gen. Virol., 22: 233.CrossRefGoogle Scholar
  26. Haseloff, J. and Gerlach, W., 1988, Simple RNA enzymes with new and highly specific endonuclease activities, Nature, 334: 585.PubMedCrossRefGoogle Scholar
  27. Heinrichs, E.A. and Rapusas, H., 1983, Correlation of resistance of the green leafhopper Nephotettix virescens (Hompoptera: Cicadellidae) with tungro virus infection in rice varieties having different genes for resistance, Environ. Entomol., 12: 201.Google Scholar
  28. Hellmann, G.M., Shaw, J.G. and Rhoads, R.E., 1988, In vitro analysis of tobacco vein mottling virus NIa cistron: evidence for a virus-encoded protease, Virology, 163: 554.PubMedCrossRefGoogle Scholar
  29. Hemenway, C., Fang, R.-X., Kaniewski, W.K., Chua, N.-H. and Turner, N.E., 1988, Analysis of the mechanism of protection in transgenic plants expressing the potato virus X coat protein or its antisense RNA, EMBO Jour., 7: 1273.Google Scholar
  30. Hibino, H., Tiongco, E.R., Cabunagan, R.C. and Flores, Z.M., 1987, Resistance to rice tungro-associated viruses in rice under experimental and natural conditions, Phytopathology, 77: 871.CrossRefGoogle Scholar
  31. Holmes, F.O., 1956, A simultaneous-infection test for viral inter-relationships as applied to aspermy and other viruses, Virology, 2: 611.PubMedCrossRefGoogle Scholar
  32. Horikoshi, M., Mise, K., Furusawa, I. and Shishiyama, J., 1988, Immunological analysis of brome mosaic virus replicase, J. gen. Virol., 69: 3081.CrossRefGoogle Scholar
  33. Hull, R., 1970, Studies on alfalfa mosaic virus. III. Reversible dissociation and reconstitution studies, Virology, 40: 34.PubMedCrossRefGoogle Scholar
  34. Hull, R., 1986, The pathogenesis of cauliflower mosaic virus, in “Genetics and Plant Pathogenesis”, P.R. Day and G.J. Jellis ed., Blackwell: Oxford, pp. 25–32.Google Scholar
  35. Hull, R., 1989, The movement of viruses in plants, Ann. Rev. Phytopath., in press.Google Scholar
  36. Loebenstein, G. and Gera, A., 1981, Inhibitor of virus replication released from tobacco mosaic virus-infected protoplasts of a local lesion-responding tobacco cultivar, Virology, 114: 132.PubMedCrossRefGoogle Scholar
  37. Meshi, T., Motoyoshi, F., Adachi, A., Watanabe, Y., Takamatsu, N. and Okada, Y., 1988, Two concomitant base substitutions in the putative replicase genes of tobacco mosaic virus confer the ability to overcome the effects of a tomato resistance gene, Tm-1, EMBO Jour., 7: 1575.Google Scholar
  38. Modjtahedi, N., Volovitch,M., Mazzolini, L. and Yot, P., 1985, Comparison of the predicted secondary structure of aphid transmission factor for transmissible and non-transmissible cauliflower mosaic virus strains, FEBS Letters, 181: 223.CrossRefGoogle Scholar
  39. Paszkowski, J., Baur, M., Bogucki, A. and Potrykus, I., 1988, Gene targetting in plants, EMBO Jour., 7: 4021.Google Scholar
  40. Ponz, F., Glascoch, C.B. and Bruening, G., 1988, An inhibitor of polyprotein processing with the characteristics of a natural virus resistance factor, Molecular Plant-Microbe Interactions, 1: 25.CrossRefGoogle Scholar
  41. Rapusas, H.R. and Heinrichs, E.A., 1982, Plant age and levels of resistance to green leafhopper, Nephotettix virescens (Distant), and tungro virus in rice cultivars, Crop Prot., 1: 91.CrossRefGoogle Scholar
  42. Register, J.C. and Beachy, R.N., 1988, Resistance to TMV in transgenic plants results from interference with an early event in infection, Virology, 166: 524.PubMedCrossRefGoogle Scholar
  43. Sanford, J.C. and Johnston, S.A., 1985, The concept of parasite-derived resistance - deriving resistance genes from the parasite’s own genome, J. theor. Biol., 113: 395.CrossRefGoogle Scholar
  44. Sela, I., Grafi, G., Sher, N., Edelbaum, O., Yagev, H. and Gerassi, E., 1987, Resistance systems related to the N gene and their comparison with interferon, in “Plant Resistance to Viruses”, CIBA Foundation Symposium 133, D. Evered and S. Harnett, eds., John Wiley and Sons, Chichester, pp. 109–119.Google Scholar
  45. Smith, C.J.S., Watson, C.F., Ray, J., Bird, C.R., Morris, P.C., Schuch, W. and Grierson, D., 1988, Antisense RNA inhibition of polygalacturonidase gene expression in transgenic tomatoes, Nature, 334: 724.CrossRefGoogle Scholar
  46. van der Krol, A.R., Lenting, P.E., Veenstra, J., van der Meer, I.M., Koes, R.E., Gerats, A.G.M., Mol, J.N.M. and Stuitje, A.R., 1988, An anti-sense chalcone synthase gene in transgenic plants inhibits flower pigmentation, Nature, 333: 866.CrossRefGoogle Scholar
  47. van Kammen, A. and Eggen, H.I.L., 1986, The replication of cowpea mosaic virus, Bio Essays, 5: 261.Google Scholar
  48. Wilson, T.M.A., 1989, Plant viruses: A tool-box for genetic engineering and crop protection, BioEssays, in press.Google Scholar
  49. Woolston, C.J., Czaplewski, L.G., Markham, P.G., Goad, A.S., Hull, R. and Davies, J.W., 1987, Location and sequence of a region of cauliflower mosaic virus gene 2 responsible for aphid transmissibility, Virology, 160: 246.CrossRefGoogle Scholar
  50. Zaitlin, M. and Hull, R., 1987, Plant virus-host interactions, Ann. Rev. Plant Physiol., 38: 291.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Roger Hull
    • 1
  1. 1.John Innes Institute and AFRC Institute of Plant Science ResearchNorwichUK

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