Chronic Non-A, Non-B Hepatitis: The Pathologist’s Perspective
A clinical diagnosis of chronic hepatitis is made when a patient has an elevation of serum aminotransferase activity that persists for 6 months or longer.1 This may follow an otherwise typical acute viral hepatitis; it may be discovered incidentally in a patient being evaluated for some other reason; or the patient may present with symptoms of chronic liver disease. Frequently in this situation, the clinician is prompted to obtain a liver biopsy to confirm the diagnosis of chronic hepatitis and to gather information about the cause, the stage of the disease, and the prognosis. This raises the question of the value of the liver biopsy in providing that information.
KeywordsChronic Hepatitis Liver Biopsy Primary Biliary Cirrhosis Bile Duct Injury Chronic Active Hepatitis
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