Primary Sclerosing Cholangitis: Histopathology

  • Jay H. Lefkowitch


Primary sclerosing cholangitis (PSC) is a chronic idiopathic fibrosing and inflammatory disease affecting the intrahepatic and extrahepatic bile ducts.1–7 Abundant data on liver pathology in PSC are now available because of the increased frequency of Cholangiographic diagnosis and availability of livers for examination from PSC patients who have undergone transplantation.8 This chapter reviews our current understanding of hepatic pathology in this condition, its differentiation from other cholestatic conditions, and the diagnostic terminology.


Bile Duct Ulcerative Colitis Primary Biliary Cirrhosis Primary Sclerosing Cholangitis Sclerosing Cholangitis 
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Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Jay H. Lefkowitch
    • 1
  1. 1.Department of Pathology, College of Physicians and SurgeonsColumbia UniversityNew YorkUSA

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