The Morphological Spectrum of Alcoholic Liver Disease

  • Lionel Rabin


It is convenient to classify the manifestations of liver disease related to alcoholism into three types: (1) alcoholic fatty liver, (2) alcoholic hepatitis, and (3) cirrhosis. Light microscopic morphologic findings in these three categories, however, may coexist or overlap.1–5 In addition, there is frequently a poor correlation between the clinical, biochemical, and morphological findings in patients with alcohol-related liver injury. Further difficulties in morphologic interpretation arise from the recognition of a variety of clinical settings or entities unrelated to alcohol ingestion that may mimic alcoholic liver disease, and from alterations superimposed on alcohol-related liver injury by causes, such as viral hepatitis, drug-induced hepatotoxicity, and biliary tract obstruction.


Fatty Liver Primary Biliary Cirrhosis Alcoholic Liver Disease Mallory Body Alcoholic Hepatitis 
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Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Lionel Rabin
    • 1
  1. 1.Hepatic PathologyArmed Forces Institute of PathologyUSA

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