Control of the Mitotic B Cell Cycle: Facts and Speculations

  • Fritz Melchers
Part of the NATO ASI Series book series (NSSA, volume 123)


During their differentiation from stem cells and precursors B lymphocytes reach a stage when they become resting. These resting B lymphocytes can be activated into cell cycle again when they meet antigen or polyclonal activators. This paper gives a synopsis of the reactions that lead to activation of B cells from the resting state and that control successive B cell cycles.


Major Histocompatibility Complex Major Histocompatibility Complex Class Restriction Point Cell Cycle Control Sister Chromatid Exchange 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Fritz Melchers
    • 1
  1. 1.Basel Institute for ImmunologyBaselSwitzerland

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