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Normal and Neoplastic B Lymphocytes Produce Interleukin-1 (IL-1) and Colony Stimulating Factor (CSF)

  • V. Pistoia
  • F. Cozzolino
  • R. Ghio
  • E. Castigli
  • M. Torcia
  • S. Zupo
  • A. Rubartelli
  • S. Roncella
  • M. Ferrarini
Part of the NATO ASI Series book series (NSSA, volume 123)

Abstract

Upon contact with antigen, T cells are activated to proliferate and to release factors that regulate B cell differentiation and also promote an inflammatory process. As discussed in previous chapters of this book, antigen has to be adsorbed and appropriately processed by accessory cells before being presented to T cells in the contest of autologous MHC products.

Keywords

Chronic Lymphocytic Leukemia Cell Chronic Lymphocytic Leukemia Accessory Cell Percoll Density Gradient Lymphokine Production 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • V. Pistoia
    • 1
    • 2
    • 3
    • 4
  • F. Cozzolino
    • 1
    • 2
    • 3
    • 4
  • R. Ghio
    • 1
    • 2
    • 3
    • 4
  • E. Castigli
    • 1
    • 2
    • 3
    • 4
  • M. Torcia
    • 1
    • 2
    • 3
    • 4
  • S. Zupo
    • 1
    • 2
    • 3
    • 4
  • A. Rubartelli
    • 1
    • 2
    • 3
    • 4
  • S. Roncella
    • 1
    • 2
    • 3
    • 4
  • M. Ferrarini
    • 1
    • 2
    • 3
    • 4
  1. 1.Servizio di Immunologia ClinicaIstituto Nazionale per la Ricerca sul CancroGenovaItaly
  2. 2.Istituto di Oncologia Clinica e SperimentaleUniversità di GenovaItaly
  3. 3.Istituto Scientifico di Medicina InternaUniversità di GenovaItaly
  4. 4.Istituto di Clinica Medica IIUniversità di FirenzeItaly

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