Regulation of Human B Cell Proliferation and Differentiation by Interleukin 2

  • Diane F. Jelinek
  • Peter E. Lipsky
Part of the NATO ASI Series book series (NSSA, volume 123)


Interleukin 2 (IL-2) was initially identified as a T cell-derived lymphokine that specifically maintains the growth of activated T cells. Recently, however, it has been demonstrated that B cells can also be induced to express receptors for IL-2 (1). Moreover, a number of functional studies have suggested that IL-2 might play a direct role in B cell activation (2,3). This contention remains controversial however since other reports have suggested that the effect of IL-2 on B cells is an indirect one resulting from an action on contaminating T cells (4).


Fluorescence Activate Cell Sorter Staphylococcus Aureus Reverse Hemolytic Plaque Assay Method Cell Separation Mitogen Assay 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Diane F. Jelinek
    • 1
  • Peter E. Lipsky
    • 1
  1. 1.Southwestern Medical SchoolUniversity of Texas Health Science CenterDallasUSA

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