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Regulation of Human B Cell Proliferation and Differentiation by Interleukin 2

  • Diane F. Jelinek
  • Peter E. Lipsky
Part of the NATO ASI Series book series (NSSA, volume 123)

Abstract

Interleukin 2 (IL-2) was initially identified as a T cell-derived lymphokine that specifically maintains the growth of activated T cells. Recently, however, it has been demonstrated that B cells can also be induced to express receptors for IL-2 (1). Moreover, a number of functional studies have suggested that IL-2 might play a direct role in B cell activation (2,3). This contention remains controversial however since other reports have suggested that the effect of IL-2 on B cells is an indirect one resulting from an action on contaminating T cells (4).

Keywords

Fluorescence Activate Cell Sorter Staphylococcus Aureus Reverse Hemolytic Plaque Assay Method Cell Separation Mitogen Assay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Diane F. Jelinek
    • 1
  • Peter E. Lipsky
    • 1
  1. 1.Southwestern Medical SchoolUniversity of Texas Health Science CenterDallasUSA

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