Rabies Viruses—Pathogenesis and Immunity

  • William H. Wunner
Part of the The Viruses book series (VIRS)


The outcome of rabies virus infection in all warm-blooded hosts, including humans, is generally fatal. For this reason, rabies virus is by far the most important rhabdovirus (member of the genus Lyssavirus) for study with regard to understanding its mode of pathogenesis and immunity. The long history of research in rabies pathogenesis beginning early in the 19th century is clear testimony of the importance continually placed on the need to better understand the nature of the disease caused by rabies virus, which in the recorded history of rabies was possibly recognized more than 4000 years ago (Steele, 1975; Miller and Nathanson, 1977), and to determine its course of development in hope of finding a means of prevention.


Rabies Virus Rabies Vaccine Human Rabies Rabies Virus Infection Rabies Virus Glycoprotein 


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • William H. Wunner
    • 1
  1. 1.The Wistar Institute of Anatomy and BiologyPhiladelphiaUSA

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