Many of the neurological problems of childhood are manifestations of static abnormalities of the central nervous system. These can be genetically determined or result from any insult to the developing brain occurring from the time of fertilization of the ovum to the end of postnatal development. The clinical manifestations may change with time; this is a function of the interaction between normal developmental processes, attempts at functional reorganization, and the specific nature of the cerebral abnormality. It is not necessarily an indication of progressive disease.
KeywordsMental Retardation Cerebral Palsy Dysmorphic Feature Severe Mental Retardation Spastic Diplegia
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