Composition of Intraocular Fluids and the Microenvironment of the Retina

  • Laszlo Z. Bito


On the basis of its embryonic derivation, morphological organization, and function, the retina must be regarded as part of the central nervous system (CNS). A unique aspect of the CNS is its ability to maintain local extracellular chemical environments that are vastly different from those of other organ systems. Our understanding of the chemical microenvironment of the brain and the mechanisms that maintain its homeostasis is largely based on studies on the composition of cerebrospinal fluid (CSF). Similar information about the retina can be gained from studies on the chemical composition of the intraocular fluids (IOFs), particularly the vitreus* adjacent to the retina, since there are no appreciable diffusion barriers between the vitreus and the extracellular fluid (ECF) of the retina.1,2


Retinal Pigment Epithelium Blood Plasma Aqueous Humor Ciliary Epithelium Posterior Chamber 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Laszlo Z. Bito
    • 1
  1. 1.College of Physicians and SurgeonsColumbia UniversityNew YorkUSA

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