Peptidergic Systems

  • Peter Schotman
  • Loes H. Schrama
  • Philippa M. Edwards

Abstract

A peptidergic system is a functionally relevant complex consisting of a cell that synthesizes and releases the peptide, a cell that responds to that peptide by some change in function, and a means whereby the peptide is transferred from its site of synthesis to its site of action. We have included in our considerations cases in which the source of the peptide is a peptidergic neuron and the target cell is nonneuronal (neuroendocrine function), in which a nonneuronally synthesized peptide acts on a peptide-sensitive neuron, and in which both the source of and target for the peptide are neuronal.

Keywords

Polypeptide Glucocorticoid Neurol Catecholamine Acetylcholine 

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References

  1. 1.
    Pearse, A. G. E., 1976, Nature 262:92–94.CrossRefGoogle Scholar
  2. 2.
    Barker, K. L., and Smith, T. G., Jr., 1980, Prog. Brain Res. 53:169–192.PubMedCrossRefGoogle Scholar
  3. 3.
    Elliott, G. R., and Barchas, J. D., 1980, Hormones and the Brain (D. De Wied and P. A. Van Keep, eds.), MTP Press, Lancaster, pp. 43–52.CrossRefGoogle Scholar
  4. 4.
    Wiegant, V. M., and Gispen, W. H., 1976, Molecular and Functional Neurobiology (W. H. Gispen, ed.), Elsevier Biomedical Press, Amsterdam, pp. 235–254.Google Scholar
  5. 5.
    Kordon, C., 1981, Adv. Physiol. Sci. 14:265–266.Google Scholar
  6. 6.
    Krieger, D. T., 1980, Adv. Physiol. Sci. 13:151–175.Google Scholar
  7. 7.
    Witter, A., and De Wied, D., 1980, Handbook of the Hypothalamus, Volume 2 (P. J. Morgane and J. Panksepp, eds.), Marcel Dekker, New York, pp. 307–451.Google Scholar
  8. 8.
    Verhoef, J., Prins, A., Veldhuis, H. D., and Witter, A., 1982, J. Neurochem. 38:1135–1138.PubMedCrossRefGoogle Scholar
  9. 9.
    Rapoport, S. I., Klee, W. A., Pettigrew, K. D., and Ohno, K., 1980, Science 207:84–86.PubMedCrossRefGoogle Scholar
  10. 10.
    De Wied, D., 1981, Adv. Physiol. Sci. 13:23–38.Google Scholar
  11. 11.
    De Kloet, E. R., Palkovits, M., and Mezey, E., 1981, Pharmacol. Ther. 12:321–351.PubMedCrossRefGoogle Scholar
  12. 12.
    Herbert, E., Birnberg, N., Civelli, O., Lissitzky, J.-C., Uhler, M., and Durring, L., 1982, Adv. Biochem. Psychopharmacol. 33:9–18.PubMedGoogle Scholar
  13. 13.
    Smyth, D. G., Zakarian, S., Deakin, J. W. F., and Massey, D. E., 1981, Peptides of the Pars Intermedia (D. Evered and G. Lawrenson, eds.), Pitman Medical, London, pp. 79–96.Google Scholar
  14. 14.
    Jackson, S., Hope, J., Estivariz, F., and Lowry, P. J., 1981, Peptides of the Pars Intermedia (D. Evered and G. Lawrenson, eds.), Pitman Medical, London, pp. 141–162.Google Scholar
  15. 15.
    Bennett, H. P. J., Brown, C. A., and Solomon, S., 1982, Brain Res. 231:454–460.CrossRefGoogle Scholar
  16. 16.
    Parish, D. C., Smyth, D. G., Normanton, J. R., and Wolstancroft, J. H., 1983, Nature 306:267–269.PubMedCrossRefGoogle Scholar
  17. 17.
    Seizinger, B. R., and Höllt, V., 1982, Adv. Biochem. Psychopharmacol. 33:27–34.PubMedGoogle Scholar
  18. 18.
    Gillies, G., and Lowry, P. J., 1982, Frontiers in Neuroendocrinology, Volume 7 (W. F. Ganong and L. Martini, eds.), Raven Press, New York, pp. 45–75.Google Scholar
  19. 19.
    Vale, W., Spiess, J., Rivier, C., and Rivier, J., 1981, Science 213:1394–1397.PubMedCrossRefGoogle Scholar
  20. 20.
    Selye, H., 1936, Br. J. Exp. Pathol. 17:234–248.Google Scholar
  21. 21.
    Pedersen, R. C., and Brownie, A. C., 1980, Proc. Natl. Acad. Sci. U.S.A. 77:2239–2243.PubMedCrossRefGoogle Scholar
  22. 22.
    Berkenbosch, F., Tilders, F. J. H., and Vermes, I., 1983, Nature 305:237–239.PubMedCrossRefGoogle Scholar
  23. 23.
    Van Ree, J. M., Bohus, B., Csontos, K. M., Gispen, W. H., Greven, H. M., Nijkamp, F. P., Opmeer, F. A., De Rotte, G. A., Van Wimersma Greidanus, T. B., Witter, A., and De Wied, D., 1981, Life Sci. 28:2875–2888.PubMedCrossRefGoogle Scholar
  24. 24.
    Swaab, D. F., and Martin, J. R., 1981, Peptides in the Pars Intermedia (D. Evered and G. Lawrenson, eds.), Pitman Medical, London, pp. 196–217.Google Scholar
  25. 25.
    Prange, A. J., Nemeroff, C. B., Lipton, M. A., Breese, G. R., and Wilson, I. C., 1978, Handbook of Psychopharmacology, Volume 13 (L. L. Iversen, S. D. Iversen, and S. H. Snyder, eds.), Plenum Press, New York, pp. 1–107.Google Scholar
  26. 26.
    De Wied, D., 1969, Frontiers in Neuroendocrinology, Volume 3 (W. F. Ganong and L. Martini, eds.), Oxford University Press, New York, pp. 97–140.Google Scholar
  27. 27.
    Swaab, D. F., 1980, Hormones and the Brain (D. De Wied and P. A. van Keep, eds.), MTP Press, Lancaster, pp. 87–100.CrossRefGoogle Scholar
  28. 28.
    Rivier, C., and Vale, W., 1983, Nature 305:325–327.PubMedCrossRefGoogle Scholar
  29. 29.
    Sterba, G., Naumann, W., and Hoheisel, G., 1980, Prog. Brain Res. 53:141–158.PubMedCrossRefGoogle Scholar
  30. 30.
    Swanson, L. W., and Sawchenko, P. E., 1983, Annu. Rev. Neurosci. 6:269–324.PubMedCrossRefGoogle Scholar
  31. 31.
    Gash, D. M., and Thomas, G. J., 1983, Trends Neurosci. 6:197–198.CrossRefGoogle Scholar
  32. 32.
    Bohus, B., 1981, Int. J. Ment. Health 9:6–44.Google Scholar
  33. 33.
    Bohus, B., Conti, L., Kovács, G. L., and Versteeg, D. H. G., 1982, Neuronal Plasticity and Memory Formation (C. A. Marsan and H. Matthies, eds.), Raven Press, New York, pp. 75–87.Google Scholar
  34. 34.
    Laczi, F., Gaffori, O., De Kloet, E. R., and De Wied, D., 1983, Brain Res. 260:342–346.PubMedCrossRefGoogle Scholar
  35. 35.
    Burbach, J. P. H., Kovács, G. L., De Wied, D., Van Nispen, J. W., and Greven, H. M., 1983, Science 22:1310–1312.CrossRefGoogle Scholar
  36. 36.
    Pearlmutter, A. F., Costatini, M. G., and Loeser, B., 1983, Peptides 4:335–341.PubMedCrossRefGoogle Scholar
  37. 37.
    Rorstad, O. P., Martin, J. B., and Terry, L. C., 1980, The Role of Peptides in Neuronal Function (J. L. Barker and T. G. Smith, Jr., eds.), Marcel Dekker, New York, pp. 573–614.Google Scholar
  38. 38.
    Knigge, K. M., Hoffman, G. E., Joseph, S. E., Scott, D. E., Sladek, C. D., and Sladek, J. R., Jr., 1980, Handbook of the Hypothalamus (P. J. Morgane and J. Panksepp, eds.), Marcel Dekker, New York, pp. 63–164.Google Scholar
  39. 39.
    Moss, R. L., and Dudley, C. A., 1980, The Role of Peptides in Neuronal Function (J. L. Barker and T. G. Smith, Jr., eds.), Marcel Dekker, New York, pp. 455–478.Google Scholar
  40. 40.
    Spiess, J., Rivier, J., and Vale, W., 1983, Nature 303:532–535.PubMedCrossRefGoogle Scholar
  41. 41.
    Watson, S.J., and Akil, H., 1981, Adv. Biochem. Psychopharmacol. 28:77–86.PubMedGoogle Scholar
  42. 42.
    Verhoef, J., Wiegant, V. M., and De Wied, D., 1982, Brain Res. 231:454–460.PubMedCrossRefGoogle Scholar
  43. 43.
    Wang, X-C., Burbach, J. P. H., Verhoef, C. J., and De Wied, D., 1983, J. Biol. Chem. 258:7942–7947.PubMedGoogle Scholar
  44. 44.
    Hughes, J., Beaumont, A., Fuentes, J. A., Malfroy, B., and Unsworth, C., 1980, J. Exp. Biol. 89:239–255.PubMedGoogle Scholar
  45. 45.
    Rossier, J., 1982, Trends Neurosci. 5:179–180.CrossRefGoogle Scholar
  46. 46.
    Stengaard-Pedersen, K., and Larsson, L.-I., 1981, Peptides 2(Suppl. 1):3–19.PubMedCrossRefGoogle Scholar
  47. 47.
    Lightman, S. L., Ninkovic, M., Hunt, S. P., and Iversen, L. L., 1983, Nature 305:235–239.PubMedCrossRefGoogle Scholar
  48. 48.
    Weber, E., Roth, K. A., and Barchas, J. D., 1981, Biochem. Biophys. Res. Commun. 103:951–958.PubMedCrossRefGoogle Scholar
  49. 49.
    Watson, S. J., and Akil, H., 1982, Adv. Biochem. Psychopharmacol. 33:35–42.PubMedGoogle Scholar
  50. 50.
    Snyder, S. H., Innis, R. B., and Corêa, F. M. A., 1980, The Role of Peptides in Neuronal Function J. L. Barker and T. G. Smith, Jr., eds.), Marcel Dekker, New York, pp. 375–389.Google Scholar
  51. 51.
    Cooper, P. E., and Martin, J. B., 1980, Ann. Neurol. 8:551–557.PubMedCrossRefGoogle Scholar
  52. 52.
    Poulain, D. A., and Wakerley, J. B., 1982, Neuroscience 7:773–808.PubMedCrossRefGoogle Scholar
  53. 53.
    Goedert, M., 1984, Trends Neurosci. 7:3–5.CrossRefGoogle Scholar
  54. 54.
    Uhl, G. R., and Snyder, S. H., 1981, Adv. Biochem. Psychopharmacol. 28:87–106.PubMedGoogle Scholar
  55. 55.
    Fernstrom, M. H., and Leeman, S. E., 1981, Adv. Physiol. Sci. 13:155–165.Google Scholar
  56. 56.
    Dao, W. P. C., Yajima, H., Uitagawa, K., and Walker, R. J., 1981, Adv. Physiol. Sci. 14:249–254.Google Scholar
  57. 57.
    Taylor, R. L., and Burt, D. R., 1982, J. Neurochem. 38:1649–1656.PubMedCrossRefGoogle Scholar
  58. 58.
    Kalivas, P. W., and Horita, A., 1980, J. Pharmacol. Exp. Ther. 212:203–210.PubMedGoogle Scholar
  59. 59.
    Quirion, R., Schults, C. W., Moody, T. W., Pert, C. B., Chase, T. N., and Donohue, T. L., 1983, Nature 303:714–716.PubMedCrossRefGoogle Scholar
  60. 60.
    Snyder, S. H., 1980, Science 209:976–983.PubMedCrossRefGoogle Scholar
  61. 61.
    Said, S. I., 1980, The Role of Peptides in Neuronal Function (J. L. Barker and T. G. Smith, Jr., eds.), Marcel Dekker, New York, pp. 351–374.Google Scholar
  62. 62.
    Bunney, B. S., Grace, A. A., Homner, D. W., and Skirboll, L. R., 1982, Adv. Biochem. Psychopharmacol. 33:429–436.PubMedGoogle Scholar
  63. 63.
    Rosenzweig, J. L., Havrankova, J., Brownstein, M., and Roth, J., 1981, Adv. Physiol. Sci. 13:175–186.Google Scholar
  64. 64.
    Oomura, Y., and Kita, H., 1981, Diabetologica 20:290–298.CrossRefGoogle Scholar
  65. 65.
    Epstein, A. N., 1981, Adv. Biochem. Psychopharmacol. 28:373–387.PubMedGoogle Scholar
  66. 66.
    Phillips, M. I., 1980, The Role of Peptides in Neuronal Function (J. L. Barker and T. G. Smith, Jr., eds.), Marcel Dekker, New York, pp. 389–430.Google Scholar
  67. 67.
    Gispen, W. H., Van Someren, H., and Schotman, P., 1981, Adv. Physiol. Sci. 13:223–231.Google Scholar
  68. 68.
    Donohue, T. L. O., and Jacobowitz, D. M., 1980, Polypeptide Hormones (R. F. Beers, Jr., ed.), Raven Press, New York, pp. 203–222.Google Scholar
  69. 69.
    Reppert, S. M., Artman, H. G., Swaminathan, S., and Fisher, D. A., 1981, Science 213:1256–1257.PubMedCrossRefGoogle Scholar
  70. 70.
    Hökfelt, T., Lundberg, J. M., Schultzberg, M., Johansson, O., Skirboll, L., Änggård, A., Fredholm, B., Hamberger, B., Pernow, B., Rehfeld, J., and Goldstein, M., 1980, Proc. R. Soc. (Lond.) [Biol.] 210:63–77.CrossRefGoogle Scholar
  71. 71.
    Jessell, T. M., 1981, Adv. Biochem. Psychopharmacol. 28:189–198.PubMedGoogle Scholar
  72. 72.
    Dichter, M. A., and Delfs, J. R., 1981, Adv. Biochem. Psychopharmacol. 28:145–157.PubMedGoogle Scholar
  73. 73.
    Olpe, H.-R., Balcar, V. J., Bittinger, H., Rink, H., and Sieber, P., 1980, Eur. J. Pharmacol. 63:127–133.PubMedCrossRefGoogle Scholar
  74. 74.
    Pittman, A. J., 1981, Adv. Physiol. Sci. 14:231–241.Google Scholar
  75. 75.
    Nicoll, R. A., Alger, B. E., and Jahr, C. E., 1980, Proc. R. Soc. (Lond.) [Biol.] 210:133–149.CrossRefGoogle Scholar
  76. 76.
    Macdonald, R. L., and Nowak, L. M., 1981, Adv. Biochem. Psychopharmacol. 28:159–173.PubMedGoogle Scholar
  77. 77.
    Fischbach, G. D., Dunlap, K., Mudge, A., and Leeman, S., 1981, Adv. Biochem. Psychopharmacol. 28:175–188.PubMedGoogle Scholar
  78. 78.
    Kelly, J. S., and Dodd, J., 1981, Adv. Biochem. Psychopharmacol. 28:133–144.PubMedGoogle Scholar
  79. 79.
    Lichtensteiger, W., and Felix, D., 1980, Neuropeptides and Neural Transmission, IBRO Monograph Series, Volume 7 (C. A. Marsan and W. Z. Traczyk, eds.), Raven Press, New York, pp. 333–338.Google Scholar
  80. 80.
    Joëls, M., and Urban, I. J. A., 1982, Neurosci. Lett. 33:79–84.PubMedCrossRefGoogle Scholar
  81. 81.
    Mühlethaler, M., Sawyer, W. H., Manning, M. M., and Dreifuss, J. J., 1983, Proc. Natl. Acad. Sci. U.S.A. 80:6713–6717.PubMedCrossRefGoogle Scholar
  82. 82.
    Versteeg, D. H. G., 1980, Pharmacol. Ther. 11:535–557.PubMedCrossRefGoogle Scholar
  83. 83.
    Moore, K. E., and Demarest, K. K., 1982, Frontiers in Neuroendocrinology, Volume 7 (W. F. Ganong and L. Martini, eds.) Raven Press, New York, pp. 161–190.Google Scholar
  84. 84.
    Kordon, C., Enjalbert, A., Hery, M., Joseph-Bravo, P. I., Rotsztejn, W., and Ruberg, M., 1980, Handbook of the Hypothalamus, Volume 2 (P. J. Morgane and J. Panksepp, eds.), Marcel Dekker, New York, pp. 253–306.Google Scholar
  85. 85.
    Kovàcs, G. L., Bohus, B., and Versteeg, D. H. G., 1980, Prog. Brain Res. 53:123–139.PubMedCrossRefGoogle Scholar
  86. 86.
    Schulz, H., Kovàcs, G. L., and Telegdy, G., 1980, Neuropeptides and Neural Transmission (C. A. Marsan and W. Z. Traczyk, eds.), Raven Press, New York, pp. 343–349.Google Scholar
  87. 87.
    Torrens, Y., Michelot, R., Beaujouan, J. C., Glowinski, J., and Bockaert, J., 1982, J. Neurochem. 38:1728–1734.PubMedCrossRefGoogle Scholar
  88. 88.
    Nathanson, J. A., 1981, Adv. Biochem. Psychopharmacol. 28:599–608.PubMedGoogle Scholar
  89. 89.
    Crowley, W. R., 1982, Neuroendocrinology 34:381–386.PubMedCrossRefGoogle Scholar
  90. 90.
    Cardinali, D. P., 1979, Trends Neurosci. 2:250–253.CrossRefGoogle Scholar
  91. 91.
    Smelik, P., 1981, Front. Horm. Res. 8:1–11.Google Scholar
  92. 92.
    Oehme, P., Hecht, K., Piesche, L., Hiese, H., Morgenstern, E., and Popper, M., 1980, Neuropeptides and Neural Transmission, IBRO Monograph Series, Volume 7 (C. A. Marsan and W. Z. Traczyk, eds.), Raven Press, New York, pp. 73–84.Google Scholar
  93. 93.
    Traczyk, W. Z., and Luczynska, M., 1980, Neuropeptides and Neural Transmission, IBRO Monograph Series, Volume 7 (C. A. Marsan and W. Z. Traczyk, eds.), Raven Press, New York, pp. 165–180.Google Scholar
  94. 94.
    Zucker, I., and Carmichael, M. S., 1981, Adv. Biochem. Psychopharmacol. 28:459–473.PubMedGoogle Scholar
  95. 95.
    Auerbach, S., and Lipton, P., 1982, J. Neurosci. 2:477–482.PubMedGoogle Scholar
  96. 96.
    McCann, S. M., 1981, Adv. Physiol. Sci. 14:121–129.Google Scholar
  97. 97.
    Wood, P. L., Cheney, D. L., and Costa, E., 1979, Neuroscience 4:1479–1484.PubMedCrossRefGoogle Scholar
  98. 98.
    Phillis, J. W., 1980, The Role of Peptides in Neuronal Function (J. L. Barker and T. G. Smith, Jr., eds.) Marcel Dekker, New York, pp. 615–652.Google Scholar
  99. 99.
    Belcher, G., and Ryall, R. W., 1977, J. Physiol. (Lond.) 272:105–119.Google Scholar
  100. 100.
    Barker, J. L., Vincent, J.-D., and MacDonald, J. F., 1980, Neuropeptides and Neural Transmission, IBRO Monograph Series, Volume 7 (C. A. Marsan and W. Z. Traczyk, eds.), Raven Press, New York, pp. 93–103.Google Scholar
  101. 101.
    Grimm-Jørgensen, Y., 1980, The Role of Peptides in Neuronal Function (J. L. Barker and T. G. Smith, Jr., eds.), Marcel Dekker, New York, pp. 479–507.Google Scholar
  102. 102.
    Reichlin, S., 1981, Adv. Biochem. Psychopharmacol. 28:573–579.PubMedGoogle Scholar
  103. 103.
    Emson, P. C., and Hunt, S. P., 1982, Molecular Approaches to Neurobiology (I. R. Brown, ed.), Academic Press, New York, pp. 255–283.Google Scholar
  104. 104.
    Pernow, B., 1980, Neuropeptides and Neural Transmission, IBRO Monograph Series, Volume 7 (C. A. Marsan and W. Z. Traczyk, eds.), Raven Press, New York, pp. 5–17.Google Scholar
  105. 105.
    Iverson, L. L., Lee, C. M., Gilbert, R. F., Hunt, S., and Emson, P. C., 1980, Proc. R. Soc. (Lond.) [Biol.] 210:91–111.CrossRefGoogle Scholar
  106. 106.
    Hökfelt, T., Lundberg, J. M., Skirboll, L., Johanssons, O., Schultzberg, M., and Vincent, S. R. 1982, Co-transmission, Proceedings of a Symposium, 50th Annual Meeting of the British Pharmacological Society, Oxford (A. C. Cuello, ed.), Macmillan, London, pp. 77–126.Google Scholar
  107. 107.
    Martin, R., and Voigt, K. H., 1981, Nature 289:502–504.PubMedCrossRefGoogle Scholar
  108. 108.
    Martin, R., Geis, R., Holl, R., Schäfer, M., and Voigt, K. H., 1983, Neuroscience 8:213–227.PubMedCrossRefGoogle Scholar
  109. 109.
    Gremlich, H. H., Fringeli, U. P., and Schwyzer, R., 1983, Biochemistry 22:4257–4264.PubMedCrossRefGoogle Scholar
  110. 110.
    Dunn, A. J., and Schotman, P., 1981, Pharmacol. Ther. 12:353–372.PubMedCrossRefGoogle Scholar
  111. 111.
    Wiegant, V. M., Zwiers, H., and Gispen, W. H., 1981, Pharmacol. Ther. 12:463–491.PubMedCrossRefGoogle Scholar
  112. 112.
    Wiegant, V. M., Reul, J. M. H. M., and Gispen, W. H., 1982, Prog. Brain Res. 56:403–410.Google Scholar
  113. 113.
    Kolata, C. B., 1978, Science 201:895–897.PubMedCrossRefGoogle Scholar
  114. 114.
    Manning, M., and Sawyer, W. H., 1984, Trends Neurosci. 7:6–9.CrossRefGoogle Scholar
  115. 115.
    Mayer, N., Saria, A., and Lembeck, F., 1980, Neuropeptides and Neural Transmission, IBRO Monograph Series, Volume 7 (C. A. Marsan and W. Z. Traczyk, eds.), Raven Press, New York, pp. 19–29.Google Scholar
  116. 116.
    Srikant, C. B., and Patel, Y. C., 1981, Endocrinology 108:341–343.PubMedCrossRefGoogle Scholar
  117. 117.
    Terenius, L., 1980, Receptors for Neurotransmitters and Peptide Hormones (C. Pepeu, M. J. Kuhar, and S. J. Enna, eds.), Raven Press, New York, pp. 321–328.Google Scholar
  118. 118.
    Pert, C. A., 1981, Adv. Biochem. Psychopharmacol. 28:117–131.PubMedGoogle Scholar
  119. 119.
    Terenius, L., 1976, Eur. J. Pharmacol. 38:211–213.PubMedCrossRefGoogle Scholar
  120. 120.
    Carter, R. J., Schuster, S., and Morley, J. S., 1979, Nature 279:74–75.PubMedCrossRefGoogle Scholar
  121. 121.
    Stengaard-Pedersen, K., and Larsson, L. I., 1981, Acta Pharmacol. Toxicol. (Kbh.) 48:39–46.CrossRefGoogle Scholar
  122. 122.
    Akil, H., Hewlett, W. A., Barchas, J. D., and Li, C. H., 1980, Eur. J. Pharmacol. 64:1–8.PubMedCrossRefGoogle Scholar
  123. 123.
    Oki, S., Nakao, K., Nakai, Y., Ling, N., and Imura, H., 1980, Eur. J. Pharmacol. 64:161–164.PubMedCrossRefGoogle Scholar
  124. 124.
    Gispen, W. H., and Isaacson, R. L., 1981, Pharmacol. Ther. 12:209–246.PubMedCrossRefGoogle Scholar
  125. 125.
    Ramachandran, J., Lee, C. Y., Keri, G., and Kenez-Keri, M., 1980, Polypeptide Hormones (R. F. Beers, Jr., ed.), Raven Press, New York, pp. 295–308.Google Scholar
  126. 126.
    Greven H. M., and De Wied, D., 1980, Hormones and the Brain (D. de Wied and P. A. van Keep, eds.), MTP Press, Lancaster, pp. 115–127.CrossRefGoogle Scholar
  127. 127.
    Saez, J. M., Morera, A. M., and Dazord, A., 1981, Adv. Cyclic Nucleotide Res. 14:563–579.PubMedGoogle Scholar
  128. 128.
    Schwandt, P., 1981, Front. Horm. Res. 8:107–121.Google Scholar
  129. 129.
    Eberle, A. N., 1980, Cellular Receptors for Hormones and Neurotransmitters (D. Schulster and A. Levitzki, eds.), John Wiley & Sons, Chichester, New York, pp. 219–231.Google Scholar
  130. 130.
    Schwartz, I. L., Huang, C.-J., Fischmann, A. J., Masar, S. K., and Wyssbrod, H. R., 1981, Dev. Endocrinol. 13:101–135.Google Scholar
  131. 131.
    Teichberg, V. I., and Blumberg, S., 1980, Cellular Receptors for Hormones and Neurotransmitters (D. Schulster and A. Levitzki, eds.), John Wiley & Sons, Chichester, New York, pp. 397–403.Google Scholar
  132. 132.
    Smith, J. R., 1981, Life Sci 28:2065–2069.PubMedCrossRefGoogle Scholar
  133. 133.
    Barbaccia, M. L., Chuang, D. M., and Costa, E., 1982, Adv. Biochem. Psychopharmacol. 33:511–518.PubMedGoogle Scholar
  134. 134.
    Schneider, D. R., Felt, B. T., and Goldman, H., 1982, Pharmacol. Biochem. Behav. 16:139–143.PubMedCrossRefGoogle Scholar
  135. 135.
    Royon, G., Noble, M., and Mudge, A.W., 1983, Nature 305:715–717.CrossRefGoogle Scholar
  136. 136.
    Von Calker, D., Löffler, F., and Hamprecht, B., 1983, J. Neurochem. 40:418–427.PubMedCrossRefGoogle Scholar
  137. 137.
    Ehrlich, Y. H., Davis, L. G., Keen, P., and Brunngraber, E. G., 1980, Life Sci. 26:1765–1772.PubMedCrossRefGoogle Scholar
  138. 138.
    Arnaud, J., Nobili, O., and Boyer, J., 1981, Biochem. Biophys. Res. Commun. 103:1167–1172.CrossRefGoogle Scholar
  139. 139.
    Bernstein, H. G., Poeggel, G., Dorn, A., Luppa, H., and Ziegler, M., 1981, Experientia 37:434–435.PubMedCrossRefGoogle Scholar
  140. 140.
    Nelson, P. G., and Brenneman, D. E., 1982, Trends Neurosci. 5:229–232.CrossRefGoogle Scholar
  141. 141.
    Thoenen, H., Barde, Y.-A., and Edgar, D., 1981, Adv. Biochem. Psychopharmacol. 28:263–273.PubMedGoogle Scholar
  142. 142.
    Burstein, D. E., and Greene, L. A., 1982, Molecular Approaches to Neurobiology (I. R. Brown, ed.), Academic Press, New York, pp. 159–177.Google Scholar
  143. 143.
    Narumi, S., and Maki, Y., 1978, J. Neurochem. 30:1321–1326.PubMedCrossRefGoogle Scholar
  144. 144.
    Martin, J. B., and Landis, D. M. D., 1981, Adv. Biochem. Psychopharmacol. 28:673–689.PubMedGoogle Scholar
  145. 145.
    Daval, J. L., Louis, J. C., Gerard, M. J., and Vincendon, G., 1983, Neurosci. Lett. 36:299–304.PubMedCrossRefGoogle Scholar
  146. 146.
    Strand, F. L., and Smith, L. M., 1980, Pharmacol. Ther. 11:509–533.PubMedCrossRefGoogle Scholar
  147. 147.
    Bijlsma, W. A., Jennekens, F. G. I., Schotman, P., and Gispen, W. H., 1981, Eur. J. Pharmacol. 76:73–79.PubMedCrossRefGoogle Scholar
  148. 148.
    Bijlsma, W. A., Jennekens, F. G. I., Schotman, P., and Gispen, W. H., 1983, Nerve Muscle 6:104–112.CrossRefGoogle Scholar
  149. 149.
    Bijlsma, W. A., van Asselt, E., Veldman, H., Jennekens, F. G. I., Schotman, P., and Gispen, W. H., 1983, Acta Neuropathol. (Berl.) 62:24–30.CrossRefGoogle Scholar
  150. 150.
    Bijlsma, W. A., Schotman, P., Jennekens, F. G. I., and Gispen, W. H., 1983, Neurosci. Lett. 38:297–302.PubMedCrossRefGoogle Scholar
  151. 151.
    Schotman, P., Allaart, J., and Gispen, W. H., 1981, Brain Res. 219:121–135.PubMedCrossRefGoogle Scholar
  152. 152.
    Gispen, W. H., and Schotman, P., 1976, Neuroendocrinology 21:97–110.PubMedCrossRefGoogle Scholar
  153. 153.
    De Wied, D., 1977, Acta Endocrinol. 85:9–19.Google Scholar
  154. 154.
    Jakoubek, B., Burešová, M., Hájek, I., Etrychova, J., Pavlik, A., and Radičová, A., 1972, Brain Res. 43:417–428.PubMedCrossRefGoogle Scholar
  155. 155.
    Reith, M. E. A., Schotman, P., and Gispen, W. H., 1977, Mechanisms, Regulation and Special Functions of Protein Synthesis in the Brain (S. Roberts, A. Lajtha, and W. H. Gispen, eds.), Elsevier Biomedical Press, Amsterdam, pp. 383–398.Google Scholar
  156. 156.
    Fekete, M., Bohus, B., and de Wied, D., 1983, Neuroendocrinology 36:112–118.PubMedCrossRefGoogle Scholar
  157. 157.
    Lando, D., and Raynaud, J. P., 1980, Endocrinology 107:2063–2068.PubMedCrossRefGoogle Scholar
  158. 158.
    Lando, D., Secchi, J., Roche, J., and Raynaud, J. P., 1980, Endocrinology 107:2055–2062.PubMedCrossRefGoogle Scholar
  159. 159.
    Schotman, P., and Allaart, J., 1981, J. Neurochem. 37:1349–1352.PubMedCrossRefGoogle Scholar
  160. 160.
    Schotman, P., van Heuven-Nolsen, D., and Gispen, W. H., 1980, J. Neurochem. 34:1661–1670.PubMedCrossRefGoogle Scholar
  161. 161.
    Schrama, L. H., Frankena, H., Edwards, P. M., and Schotman, P., 1984, J. Neurosci. Res. 11:67–77.PubMedCrossRefGoogle Scholar
  162. 162.
    Schrama, L. H., Weeda, E., Frankena, H., Edwards, P. M., and Schotman, P., 1983, 15th FEBS Meeting, Elsevier Sci. Publ., Amsterdam, p. 284.Google Scholar
  163. 163.
    Zomzely-Neurath, C. E., and Walker, W. A., 1980, Proteins of the Nervous System (R. A. Bradshaw and D. M. Schneider, eds.), Raven Press, New York, pp. 1–57.Google Scholar
  164. 164.
    Hydén, H., 1976, Prog. Brain Res. 45:83–100.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Peter Schotman
    • 1
  • Loes H. Schrama
    • 1
  • Philippa M. Edwards
    • 1
  1. 1.Division of Molecular Neurobiology, Institute of Molecular Biology, Laboratory of Physiological Chemistry and Rudolf Magnus Institute for PharmacologyState University of UtrechtUtrechtThe Netherlands

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