Thyroid Hormones

  • Jacques Nunez


The bulk of information accumulated during the past 30 years has confirmed that thyroid hormones exert direct effects on brain organization and function. Most of the brain abnormalities observed as a consequence of early hypothyroidism both in humans and experimental animals are permanent: they are reversed only if early replacement therapy with adequate amounts of thyroid hormones is performed. Thyroid hormones appear to be a major epigenic factor, which allows the innate developmental program to be accomplished.


Thyroid Hormone Purkinje Cell Thyroid Gland Brain Development Parallel Fiber 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Jacques Nunez
    • 1
  1. 1.Unité de Recherche 35 de l’INSERM, and Equipe de Recherche sur la Biochimie de la Régulation Hormonale, CNRSHopital H. Mondor94 CreteilFrance

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