B Virus (Herpesvirus simiae)

  • Hanns Ludwig
  • G. Pauli
  • H. Gelderblom
  • G. Darai
  • H.-G. Koch
  • R. M. Flüge
  • B. Norrild
  • M. D. Daniel
Part of the The Viruses book series (VIRS)


The early studies on the B virus (Herpesvirus simiae, herpesvirus B, simian herpesvirus, cercopithecine herpesvirus 1) are associated with the names of such pioneers in medical virology as Sabin and Wright (1934), Sabin (1934a-c), Burnet et al. (1939a,b), Melnick and Banker (1954), and Youngner (1956). In the 1930s, the virus was isolated and its cross-neutralization with herpes simplex virus (HSV) discovered. Some biological and morphological parameters were established in the 1950s. It was almost half a century, however, before the genetic material of the B virus could be characterized to allow for a clear differentiation from HSV and before the antigenic cross-reactivity with HSV and the bovine herpes mammillitis virus [bovid herpesvirus 2 (BHV-2)] could be pinpointed to major glycoprotein species (Sterz et al., 1973–1974; Ludwig et al.,1978; Norrild et al., 1978b; Pauli et al., 1981; and further details presented in this review).


Rhesus Monkey Herpes Simplex Virus Type Plex Virus Intranuclear Inclusion Body Herpesvirus Saimiri 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Hanns Ludwig
    • 1
  • G. Pauli
    • 1
  • H. Gelderblom
    • 2
  • G. Darai
    • 3
  • H.-G. Koch
    • 3
  • R. M. Flüge
  • B. Norrild
    • 4
  • M. D. Daniel
    • 5
  1. 1.Institut für VirologieFreie Universität BerlinWest BerlinGermany
  2. 2.Robert Koch-Institut des Bundesgesundheit samtesWest BerlinGermany
  3. 3.Institut fur Medizin-ische VirologieUniversität HeidelbergHeidelbergGermany
  4. 4.Institute of Medical MicrobiologyUniversity of CopenhagenCopenhagenDenmark
  5. 5.New England Regional Primate Research CenterHarvard Medical SchoolSouthboroughUSA

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