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Functions of DNA Polymerases α, β and γ in DNA Replication and Repair

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Lymphocyte Stimulation

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Abstract

The cells of vertebrate organisms contain three distinct DNA polymerases which have been designed α, β and γ -polymerases (1). The information concerning the physical, chemical and catalytical properties of these enzymes has progressed considerably during the past few years so that the distinction of their activities is easily obtained by utilizing the differences in molecular weight, sensitivity to inhibitors, chromatographic elution, ability to copy various templates (reviews: 2–8). The general properties of the three enzymes are summarized in Table I.

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Authors and Affiliations

  1. Laboratorio di Genetica Biochimica ed Evoluzionistica, Consiglio Nazionale delle Ricerche, Via S. Epifanio 14, 27100, Pavia, Italy

    Miria Stefanini, Anna I. Scovassi & Umberto Bertazzoni

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  1. Miria Stefanini
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  2. Anna I. Scovassi
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  3. Umberto Bertazzoni
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Editors and Affiliations

  1. Division of Radiation Protection, CNEN - CSN Casaccia, Rome, Italy

    Amleto Castellani

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© 1980 Plenum Press, New York

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Stefanini, M., Scovassi, A.I., Bertazzoni, U. (1980). Functions of DNA Polymerases α, β and γ in DNA Replication and Repair. In: Castellani, A. (eds) Lymphocyte Stimulation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-6997-4_3

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  • DOI: https://doi.org/10.1007/978-1-4684-6997-4_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-6999-8

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