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DNA Replication Units in Eukaryotes

  • Francesco Amaldi

Abstract

The eukaryotic chromosome contains a single DNA molecule whose length ranges, in different organisms and different individual chromosomes, from few mm up to the order of 1 m. Very simple calculations show that a DNA molecule of such astonishing size cannot replicate starting from a unique origin and proceeding at one or two (bidirectional) replication forks as it occurs in prokaryotic chromosomes and in the small DNA molecules of plasmids, viruses etc.

Keywords

Chinese Hamster Cell Okazaki Fragment Replication Unit Urchin Paracentrotus Lividus Parental Strand 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Francesco Amaldi
    • 1
  1. 1.Centro di Studio per gli Acidi Nucleici, C.N.R. Istituto di Fisiologia GeneraleUniversità di RomaItaly

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