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Enzyme Activity at a Gas Solid Interphase: Oxidation of Methanol to Formaldehyde

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Enzyme Engineering

Abstract

Methanol-consuming yeasts have an FAD-dependent methanol oxidase, which catalyzes the reaction between methanol and oxygen to form formaldehyde and hydrogen peroxide. The catalâse that is present in the same peroxisomes decomposes the hydrogen peroxide; it also acts as a formaldehyde producer by oxidation of the methanol (1,2). A subsequent enzymatic step incorporates formaldehyde into different metabolic pathways through an NADH2 - dependent formaldehyde dehydrogenase, which requires a mechanism for NAD regeneration. Therefore, non-viable cells will not decompose formaldehyde since the NAD cannot be regenerated (1).

Presented by J. Limon-Lason

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References

  1. KATO, N., TANI, Y., & OGATA, K. Agn. Biol. Chem. 38: 675, 1974.

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  2. SABAIO, F., ATSUO, T., SUSUMA, K., SHIGEKI, Y., YUTAKA, T., & MASAKO, O. J. Bacteniol. 123: 317, 1975.

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  3. ZUNIGA, V. M.S. Thesis, CIEA del IPN; Mexico, 1977.

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  4. SAHM, H., B. DIX. L. EGGELING & R. ROGGENKAMP. Abst. 5th Intenn. Fenment. Symp., Berlin, 1976.

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  5. WALKER, F. “Formaldehyde,” 3rd Edit., Reinhold, New York, 1966, p. 469.

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  6. VOGEL, A.I. “A Textbook of Practical Organic Chemistry Including Qualitative Organic Analysis,” 3rd Edit., Longmans, New York, 1962, p. 325.

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  7. HELMKAMP, H. “Sinopsis de Quimica Organica,” 2nd Edit., McGraw-Hill, New York, 1968, p. 68.

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Author information

Authors and Affiliations

  1. Centro de Investigacion y Estudios Avanzados, Instituto Politecnico Nacional, Mexico, D.F., Mexico

    Miguel Cedeno & Mario Waissbluth

Authors
  1. Miguel Cedeno
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  2. Mario Waissbluth
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Editor information

Editors and Affiliations

  1. Départment de Génie Biologique, Université de Technologie, Compiègne, France

    Georges B. Broun

  2. Institut für Organische Chemie, Freie Universität Berlin, Berlin, Federal Republic of Germany

    Georg Manecke

  3. Department of Pharmacology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Lemuel B. Wingard Jr.

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© 1978 Plenum Press, New York

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Cedeno, M., Waissbluth, M. (1978). Enzyme Activity at a Gas Solid Interphase: Oxidation of Methanol to Formaldehyde. In: Broun, G.B., Manecke, G., Wingard, L.B. (eds) Enzyme Engineering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-6985-1_82

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  • DOI: https://doi.org/10.1007/978-1-4684-6985-1_82

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-6987-5

  • Online ISBN: 978-1-4684-6985-1

  • eBook Packages: Springer Book Archive

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